Featured Publications
Cerebellar Hippocampal and Basal Nuclei Transient Edema with Restricted diffusion (CHANTER) Syndrome
Jasne AS, Alsherbini KH, Smith MS, Pandhi A, Vagal A, Kanter D. Cerebellar Hippocampal and Basal Nuclei Transient Edema with Restricted diffusion (CHANTER) Syndrome. Neurocritical Care 2019, 31: 288-296. PMID: 30788708, PMCID: PMC6757017, DOI: 10.1007/s12028-018-00666-4.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcoholic IntoxicationAmphetaminesBasal GangliaBenzodiazepinesBrain EdemaCentral Nervous System StimulantsCerebellar CortexCerebellumCocaineComaFemaleHeroinHippocampusHumansHydrocephalusHydromorphoneMagnetic Resonance ImagingMaleMiddle AgedOpiate AlkaloidsPain, PostoperativeStuporSubstance-Related DisordersSyndromeConceptsCerebellar edemaIschemic strokeObstructive hydrocephalusCerebellar cortexAcute cytotoxic edemaSeries of patientsNeurocritical care unitPatterns of injuryLevel of consciousnessMagnetic resonance imagingClinical characteristicsInitial presentationCare unitSurgical managementHypoxic injuryCytotoxic edemaFavorable outcomeSimilar presentationAnoxic injuryBilateral hippocampusTransient edemaBasal nucleusToxic injuryNovel syndromeAcceptable outcomes
2024
Adjunctive Intravenous Argatroban or Eptifibatide for Ischemic Stroke
Adeoye O, Broderick J, Derdeyn C, Grotta J, Barsan W, Bentho O, Berry S, Concha M, Davis I, Demel S, Elm J, Gentile N, Graves T, Hoffman M, Huang J, Ingles J, Janis S, Jasne A, Khatri P, Levine S, Majjhoo A, Panagos P, Pancioli A, Pizzella S, Ranasinghe T, Sabagha N, Sivakumar S, Streib C, Vagal A, Wilson A, Wintermark M, Yoo A, Barreto A. Adjunctive Intravenous Argatroban or Eptifibatide for Ischemic Stroke. New England Journal Of Medicine 2024, 391: 810-820. PMID: 39231343, PMCID: PMC11528349, DOI: 10.1056/nejmoa2314779.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnticoagulantsArginineCombined Modality TherapyDrug Therapy, CombinationEptifibatideFemaleFibrinolytic AgentsHumansIncidenceInfusions, IntravenousIntracranial HemorrhagesIschemic StrokeMaleMiddle AgedPeptidesPipecolic AcidsPlatelet Aggregation InhibitorsSingle-Blind MethodSulfonamidesThrombectomyThrombolytic TherapyTreatment OutcomeConceptsSymptomatic intracranial hemorrhageIntravenous argatrobanIntravenous thrombolysisAcute ischemic strokeIntracranial hemorrhageIschemic strokeIncidence of symptomatic intracranial hemorrhageSymptom onsetIschemic stroke treated with intravenous thrombolysisAcute ischemic stroke treated with intravenous thrombolysisStroke treated with intravenous thrombolysisAssociated with increased mortalityRankin Scale scoreInitiation of thrombolysisControlled clinical trialsTreatment of acute ischemic strokePlacebo groupEptifibatide groupEfficacy outcomesArgatroban groupStandard treatmentAdjunctive treatmentPlaceboClinical trialsArgatrobanTemporal Trends and Racial Disparities in Long-Term Survival After Stroke
Robinson D, Ding L, Howard G, Stanton R, Khoury J, Sucharew H, Haverbusch M, Nobel L, Khatri P, Adeoye O, Broderick J, Ferioli S, Mackey J, Woo D, Rios La Rosa F, Flaherty M, Slavin S, Star M, Martini S, Demel S, Walsh K, Coleman E, Jasne A, Mistry E, Kleindorfer D, Kissela B. Temporal Trends and Racial Disparities in Long-Term Survival After Stroke. Neurology 2024, 103: e209653. PMID: 39008784, PMCID: PMC11249510, DOI: 10.1212/wnl.0000000000209653.Peer-Reviewed Original ResearchConceptsPremorbid functional statusFunctional statusRacial disparitiesAcute ischemic strokeBlack individualsPopulation-based stroke studyBlack raceEffect of black raceNational Death IndexAssociated with 5-year mortalityBaseline functional statusAcute ischemic stroke casesRisk of deathPhysician adjudicationIntracerebral hemorrhageDeath IndexIntracerebral hemorrhage casesUS populationICD codesGeneral populationCalendar yearLogistic regressionModified Rankin ScaleStroke StudyMedical recordsHealth Factors Associated With Development and Severity of Poststroke Dysphagia: An Epidemiological Investigation
Krekeler B, Schieve H, Khoury J, Ding L, Haverbusch M, Alwell K, Adeoye O, Ferioloi S, Mackey J, Woo D, Flaherty M, La Rosa F, Demel S, Star M, Coleman E, Walsh K, Slavin S, Jasne A, Mistry E, Kleindorfer D, Kissela B. Health Factors Associated With Development and Severity of Poststroke Dysphagia: An Epidemiological Investigation. Journal Of The American Heart Association 2024, 13: e033922. PMID: 38533959, PMCID: PMC11179757, DOI: 10.1161/jaha.123.033922.Peer-Reviewed Original ResearchConceptsHistory of high cholesterolDysphagia statusLogistic regressionFactors associated with reduced riskHealth risk factorsPopulation-based studyFactors associated with increased riskNational Institutes of Health Stroke Scale scoreMultivariate logistic regressionRisk of dysphagiaPoststroke dysphagiaHemorrhagic stroke casesStroke Scale scoreStroke casesDevelopment of dysphagiaStroke recoveryPercutaneous endoscopic gastrostomy tube placementBlack raceRight hemisphere strokeHemorrhagic strokeHigh cholesterolRisk factorsAcute strokeFactors associated with developmentChart review