2024
Migraine May Represent an Independent Risk Factor for Retinal Stroke: A Population-Based Cohort Study
Lusk J, Song A, Unnithan S, Al-Khalidi H, de Havenon A, Biousse V, Schrag M, Solopova E, Poli S, Osazuwa-Peters N, Xian Y, O'Brien E, Mac Grory B. Migraine May Represent an Independent Risk Factor for Retinal Stroke: A Population-Based Cohort Study. Clinical Neurology And Neurosurgery 2024, 246: 108587. PMID: 39405806, PMCID: PMC11527560, DOI: 10.1016/j.clineuro.2024.108587.Peer-Reviewed Original ResearchRetinal artery occlusionRetinal strokeRisk factorsCohort studyPopulation-based cohort studyState Emergency Department DatabasesPopulation-based dataEmergency Department DatabasesCause-specific hazard modelBurden of atrial fibrillationCongestive cardiac failureIndependent risk factorChronic kidney diseasePrimary exposureDepartment databasePrimary endpointSecondary endpointsCardiac failureAtrial fibrillationHazards modelRobust associationsArtery occlusionKidney diseaseMigraineDiagnostic positions
2021
Increased Blood Pressure Variability and the Risk of Probable Dementia or Mild Cognitive Impairment: A Post Hoc Analysis of the SPRINT MIND Trial
de Havenon A, Anadani M, Prabhakaran S, Wong K, Yaghi S, Rost N. Increased Blood Pressure Variability and the Risk of Probable Dementia or Mild Cognitive Impairment: A Post Hoc Analysis of the SPRINT MIND Trial. Journal Of The American Heart Association 2021, 10: e022206. PMID: 34533059, PMCID: PMC8649507, DOI: 10.1161/jaha.121.022206.Peer-Reviewed Original ResearchConceptsBlood pressure controlBlood pressure variabilityMild cognitive impairmentCognitive impairmentProbable dementiaMIND trialBlood pressurePressure variabilityExcellent blood pressure controlPressure controlSuboptimal blood pressure controlSystolic blood pressure variabilityCox proportional hazards modelRisk of dementiaBlood pressure measurementsProportional hazards modelRate of dementiaPost Hoc AnalysisLowest tertileHighest tertilePrimary outcomeCardiovascular diseaseHoc AnalysisCox modelHazards model
2020
Diabetic Retinopathy and Risk of Stroke
Wong KH, Hu K, Peterson C, Sheibani N, Tsivgoulis G, Majersik JJ, de Havenon AH. Diabetic Retinopathy and Risk of Stroke. Stroke 2020, 51: 3733-3736. PMID: 33019896, PMCID: PMC7686117, DOI: 10.1161/strokeaha.120.030350.Peer-Reviewed Original ResearchConceptsBlood pressure interventionsRisk of strokeDiabetic retinopathyRandomization armIncident strokePrimary outcomePressure interventionPresence of DRCox proportional hazards modelACCORD Eye StudyRapid vision lossSubsequent stroke eventsCommon microvascular complicationCox regression modelProportional hazards modelMacrovascular complicationsMicrovascular complicationsHazard ratioEye StudyMicrovascular pathologyStroke eventsStudy baselineSerum glucoseVision lossHazards model