2019
CHA2DS2-VASc Score and In-Hospital Mortality in Critically Ill Patients With New-Onset Atrial Fibrillation
Karamchandani K, Schoaps RS, Abendroth T, Carr ZJ, King TS, Bonavia A. CHA2DS2-VASc Score and In-Hospital Mortality in Critically Ill Patients With New-Onset Atrial Fibrillation. Journal Of Cardiothoracic And Vascular Anesthesia 2019, 34: 1165-1171. PMID: 31899140, DOI: 10.1053/j.jvca.2019.11.044.Peer-Reviewed Original ResearchConceptsNew-onset atrial fibrillationIntensive care unitTertiary care academic institutionHospital mortalityVASc scoreAtrial fibrillationIll patientsAdult patientsVascular diseasePrognostic markerTertiary care academic medical centerAssociation of CHAConcomitant vascular diseaseHospital mortality rateIn-Hospital MortalitySingle-center studyReliable prognostic markersAcademic medical centerElectronic medical recordsCHA2DS2-VAScHospital deathCare unitMedical recordsRetrospective analysisMedical CenterPost‐operative intensive care unit admission after elective non‐cardiac surgery: A single‐center analysis of the NSQIP database
Bruceta M, De Souza L, Carr ZJ, Bonavia A, Kunselman AR, Karamchandani K. Post‐operative intensive care unit admission after elective non‐cardiac surgery: A single‐center analysis of the NSQIP database. Acta Anaesthesiologica Scandinavica 2019, 64: 319-328. PMID: 31710692, DOI: 10.1111/aas.13504.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAdultAgedBody Mass IndexCohort StudiesCritical CareDatabases, FactualElective Surgical ProceduresFemaleHospital MortalityHumansIntensive Care UnitsLength of StayMaleMiddle AgedOperative TimePatient AdmissionPennsylvaniaPostoperative ComplicationsReoperationRisk FactorsSurgical Procedures, OperativeTertiary Care CentersConceptsElective non-cardiac surgeryPost-operative ICU admissionNon-cardiac surgeryIntensive care unitBody mass indexElevated body mass indexCurrent Procedural TerminologyICU admissionACS-NSQIPDisseminated cancerPost-operative intensive care unit admissionIntensive care unit admissionTertiary care academic medical centerLonger hospital lengthSurgery-specific characteristicsCare unit admissionObservational cohort studySingle-center analysisMultivariable logistic regressionICD-9 codesLonger procedure durationAcademic medical centerDisease billing codeHospital mortalityUnit admission
2018
Continuation of atypical antipsychotic medications in critically ill patients discharged from the hospital: a single-center retrospective analysis
Karamchandani K, Schoaps RS, Bonavia A, Prasad A, Quintili A, Lehman EB, Carr ZJ. Continuation of atypical antipsychotic medications in critically ill patients discharged from the hospital: a single-center retrospective analysis. Therapeutic Advances In Drug Safety 2018, 10: 2042098618809933. PMID: 31019677, PMCID: PMC6463330, DOI: 10.1177/2042098618809933.Peer-Reviewed Original ResearchIntensive care unitAtypical antipsychoticsHospital dischargeMale sexRisk factorsSingle-center retrospective chart analysisSingle-center retrospective analysisTertiary care academic medical centerAdult intensive care unitsRisk of continuationSignificant adverse eventsRetrospective chart analysisAssociated risk factorsIntensive care settingAtypical antipsychotic medicationsYears of ageAcademic medical centerLong-term riskLong-term useAAP therapyCause mortalityAdult patientsAdverse eventsOlder patientsICU patientsCritical Care Pain Management in Patients Affected by the Opioid Epidemic: A Review
Karamchandani K, Carr Z, Bonavia A, Tung A. Critical Care Pain Management in Patients Affected by the Opioid Epidemic: A Review. Annals Of The American Thoracic Society 2018, 15: 1016-1023. DOI: 10.1513/annalsats.201801-028cme.Peer-Reviewed Original ResearchIntensive care unitOpioid dependenceOpioid epidemicLong-term opioid dependenceOpioid-related complicationsOpioid-tolerant patientsCritical care physiciansCritical care communitySufficient analgesiaICU carePain managementCare physiciansCare unitICU physiciansOpioid overdosesClinicians' attentionPatientsDirect careCare communityPhysiciansCareEpidemicDeleterious impactAnalgesiaOpioidsCritical Care Pain Management in Patients Affected by the Opioid Epidemic: A Review
Karamchandani K, Carr ZJ, Bonavia A, Tung A. Critical Care Pain Management in Patients Affected by the Opioid Epidemic: A Review. Annals Of The American Thoracic Society 2018, 15: 1016-1023. PMID: 29812953, DOI: 10.1513/annalsats.201801-028fr.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsIntensive care unitOpioid dependenceOpioid epidemicLong-term opioid dependenceOpioid-related complicationsOpioid-tolerant patientsCritical care physiciansCritical care communitySufficient analgesiaICU carePain managementCare physiciansCare unitICU physiciansOpioid overdosesClinicians' attentionPatientsDirect careCare communityPhysiciansCareEpidemicDeleterious impactAnalgesiaOpioidsIncreased whole blood FFA2/GPR43 receptor expression is associated with increased 30-day survival in patients with sepsis
Carr ZJ, Van De Louw A, Fehr G, Li JD, Kunselman A, Ruiz-Velasco V. Increased whole blood FFA2/GPR43 receptor expression is associated with increased 30-day survival in patients with sepsis. BMC Research Notes 2018, 11: 41. PMID: 29338778, PMCID: PMC5771199, DOI: 10.1186/s13104-018-3165-4.Peer-Reviewed Original ResearchConceptsRNA expressionIntensive care unit admissionBlood white cell countCare unit admissionOdds of mortalityDiagnosis of sepsisBody mass indexIntensive care unitWhite cell countGPR43 expressionUnit admissionOne-unit increaseCare unitMass indexSignificant morbidityQuantitative real-time PCRGPR43 receptorInflammatory responseImmunomodulatory pathwaysReceptor 43Receptor expressionReal-time PCRSepsisCell countPatients