2024
Prenatal arsenic metabolite exposure is associated with increased newborn mitochondrial DNA copy number: evidence from a birth cohort study
Qiu F, Zhang H, Wang X, Jia Z, He Y, Wu Y, Li Z, Zheng T, Xia W, Xu S, Li Y. Prenatal arsenic metabolite exposure is associated with increased newborn mitochondrial DNA copy number: evidence from a birth cohort study. Environmental Science And Pollution Research 2024, 31: 38142-38152. PMID: 38789711, DOI: 10.1007/s11356-024-32933-7.Peer-Reviewed Original ResearchDNA copy numberThird trimesterUrinary arsenic species concentrationsNewborn mitochondrial DNA copy numberMother-newborn pairsDose-response trendMitochondria DNA copy numberReal-time polymerase chain reactionBirth cohort studyMetabolite exposureCopy numberMitochondrial DNA copy numberOne-unit incrementCovariate-adjusted modelsBlood mtDNAcnQuantitative real-time polymerase chain reactionPolymerase chain reactionCohort studyTrimesterMetabolite levelsPotential associationStatistical significanceArsenic metabolitesChain reactionMtDNAcn
2023
Urinary biomarkers of exposure to organophosphate, pyrethroid, neonicotinoid insecticides and oxidative stress: A repeated measurement analysis among pregnant women
Wang A, Wan Y, Qi W, Mahai G, Qian X, Zheng T, Li Y, Xu S, Xiao H, Xia W. Urinary biomarkers of exposure to organophosphate, pyrethroid, neonicotinoid insecticides and oxidative stress: A repeated measurement analysis among pregnant women. The Science Of The Total Environment 2023, 912: 169565. PMID: 38145670, DOI: 10.1016/j.scitotenv.2023.169565.Peer-Reviewed Original ResearchOS biomarkersPregnant womenOxidative stressExposure biomarkersInsecticide metabolitesInadequate weight gainUrine samplesChinese pregnant womenHigher urinary levelsMetabolites of pyrethroidsGestational exposureUrinary levelsUrinary biomarkersHNE-MAMixed model analysisMetabolites of organophosphatesPercent changeWeight gainHigher education levelLipid peroxidationElevated levelsVulnerable populationsBiomarkersWomenTrimesterAssociations of Trimester-Specific Exposure to Perchlorate, Thiocyanate, and Nitrate with Childhood Neurodevelopment: A Birth Cohort Study in China
Li J, Tu F, Wan Y, Qian X, Mahai G, Wang A, Ma J, Yang Z, Xia W, Xu S, Zheng T, Li Y. Associations of Trimester-Specific Exposure to Perchlorate, Thiocyanate, and Nitrate with Childhood Neurodevelopment: A Birth Cohort Study in China. Environmental Science And Technology 2023, 57: 20480-20493. PMID: 38015815, DOI: 10.1021/acs.est.3c06013.Peer-Reviewed Original ResearchMental Development IndexOffspring neurodevelopmentMaternal exposureQuantile sum regression analysesTrimester-specific analysesTrimester-specific exposureBirth cohort studyRegression analysisBayesian kernel machine regression (BKMR) analysisCohort studyEarly pregnancyFirst trimesterSecond trimesterPrenatal exposureChildhood neurodevelopmentUrinary thiocyanateBirth cohortTrimesterNeurodevelopmentUrine samplesSensitive windowExposureAssociationMixture exposurePoint decrease