2015
Elevated follicular helper T Cells and expression of IL-21 in thyroid tissues are involved in the pathogenesis of Graves’ disease
Zhang J, Ren M, Zeng H, Guo Y, Zhuang Z, Feng Z, Yan H, Xu M, Liang W, Yang C, Cheng H, Ding H, Yan L. Elevated follicular helper T Cells and expression of IL-21 in thyroid tissues are involved in the pathogenesis of Graves’ disease. Immunologic Research 2015, 62: 163-174. PMID: 25894310, DOI: 10.1007/s12026-015-8647-z.Peer-Reviewed Original ResearchConceptsGD thyroid tissuesExpression of TfhFollicular helper T cellsThyroid follicular cellsPresence of TFHIL-21Helper T cellsThyroid tissueTSAb stimulationThyroid autoantibodiesIL-21RT cellsCAMP productionIL-21 stimulationPathogenesis of GDPathogenesis of GravesRelated factorsReal-time polymerase chain reactionNormal thyroid follicular cellsNormal thyroid tissueSerum levelsAutoimmune diseasesConfocal microscopyPolymerase chain reactionTfh
2011
Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis
Takeda Y, Costa S, Delamarre E, Roncal C, Leite de Oliveira R, Squadrito ML, Finisguerra V, Deschoemaeker S, Bruyère F, Wenes M, Hamm A, Serneels J, Magat J, Bhattacharyya T, Anisimov A, Jordan BF, Alitalo K, Maxwell P, Gallez B, Zhuang ZW, Saito Y, Simons M, De Palma M, Mazzone M. Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis. Nature 2011, 479: 122-126. PMID: 21983962, PMCID: PMC4659699, DOI: 10.1038/nature10507.Peer-Reviewed Original ResearchDevelopment and Application of a Multimodal Contrast Agent for SPECT/CT Hybrid Imaging
Criscione JM, Dobrucki LW, Zhuang ZW, Papademetris X, Simons M, Sinusas AJ, Fahmy TM. Development and Application of a Multimodal Contrast Agent for SPECT/CT Hybrid Imaging. Bioconjugate Chemistry 2011, 22: 1784-1792. PMID: 21851119, PMCID: PMC3204385, DOI: 10.1021/bc200162r.Peer-Reviewed Original Research