2008
Proteomic analysis of androgen-independent growth in low and high passage human LNCaP prostatic adenocarcinoma cells
Youm YH, Kim S, Bahk YY, Yoo TK. Proteomic analysis of androgen-independent growth in low and high passage human LNCaP prostatic adenocarcinoma cells. BMB Reports 2008, 41: 722-727. PMID: 18959819, DOI: 10.5483/bmbrep.2008.41.10.722.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAndrogensCell ExtractsCell Line, TumorCell ProliferationClone CellsDoxazosinElectrophoresis, Gel, Two-DimensionalGene Expression Regulation, NeoplasticGene SilencingHumansMaleNeoplasm ProteinsProstatic NeoplasmsProteomeProteomicsReceptors, AndrogenRNA, MessengerRNA, Small InterferingConceptsAndrogen-independent growthAndrogen-independent phenotypeProstatic adenocarcinoma cellsAndrogen receptorLNCaP cellsLow passage numberReceptor productionAdenocarcinoma cellsCell clonesProtein expressionExpression levelsPassage numberPresent studyCellsProteomic characteristicsProteomic analysisAndrogensExpressionProgression
2007
Doxazosin-induced clusterin expression and apoptosis in prostate cancer cells
Youm YH, Yang H, Yoon YD, Kim DY, Lee C, Yoo TK. Doxazosin-induced clusterin expression and apoptosis in prostate cancer cells. Urologic Oncology Seminars And Original Investigations 2007, 25: 483-488. PMID: 18047956, DOI: 10.1016/j.urolonc.2007.02.010.Peer-Reviewed Original ResearchConceptsProstate cancer cellsAndrogen-independent human prostate cancer cellsCancer cellsHuman prostate cancer cellsTranscriptase-polymerase chain reactionNick-end labeling assayMicroM doxazosinDegree of apoptosisDNA fragmentationDoxazosin treatmentClusterin mRNA expressionPolymerase chain reactionDoxazosin-induced apoptosisClusterin expressionMRNA expressionPC3 cellsPresence of clusterinClusterin mRNAChain reactionClusterinApoptotic cellsLabeling assaysDoxazosinApoptosis
2005
Less Keratinocyte-Derived Factors Related to More Keratinocyte Apoptosis in Depigmented than Normally Pigmented Suction-Blistered Epidermis May Cause Passive Melanocyte Death in Vitiligo
Lee AY, Kim NH, Choi WI, Youm YH. Less Keratinocyte-Derived Factors Related to More Keratinocyte Apoptosis in Depigmented than Normally Pigmented Suction-Blistered Epidermis May Cause Passive Melanocyte Death in Vitiligo. Journal Of Investigative Dermatology 2005, 124: 976-983. PMID: 15854039, DOI: 10.1111/j.0022-202x.2005.23667.x.Peer-Reviewed Original Research
2004
Keratinocytes in the depigmented epidermis of vitiligo are more vulnerable to trauma (suction) than keratinocytes in the normally pigmented epidermis, resulting in their apoptosis
Lee A, Youm Y, Kim N, Yang H, Choi W. Keratinocytes in the depigmented epidermis of vitiligo are more vulnerable to trauma (suction) than keratinocytes in the normally pigmented epidermis, resulting in their apoptosis. British Journal Of Dermatology 2004, 151: 995-1003. PMID: 15541077, DOI: 10.1111/j.1365-2133.2004.06136.x.Peer-Reviewed Original ResearchAdolescentAdultApoptosisBcl-2-Associated X ProteinCASP8 and FADD-Like Apoptosis Regulating ProteinCaspasesChildEpidermisFemaleHumansIntracellular Signaling Peptides and ProteinsKeratinocytesMaleMiddle AgedPoly(ADP-ribose) PolymerasesProto-Oncogene Proteins c-bcl-2SuctionTumor Suppressor Protein p53Vitiligo