2008
Proteomic analysis of androgen-independent growth in low and high passage human LNCaP prostatic adenocarcinoma cells
Youm YH, Kim S, Bahk YY, Yoo TK. Proteomic analysis of androgen-independent growth in low and high passage human LNCaP prostatic adenocarcinoma cells. BMB Reports 2008, 41: 722-727. PMID: 18959819, DOI: 10.5483/bmbrep.2008.41.10.722.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAndrogensCell ExtractsCell Line, TumorCell ProliferationClone CellsDoxazosinElectrophoresis, Gel, Two-DimensionalGene Expression Regulation, NeoplasticGene SilencingHumansMaleNeoplasm ProteinsProstatic NeoplasmsProteomeProteomicsReceptors, AndrogenRNA, MessengerRNA, Small InterferingConceptsAndrogen-independent growthAndrogen-independent phenotypeProstatic adenocarcinoma cellsAndrogen receptorLNCaP cellsLow passage numberReceptor productionAdenocarcinoma cellsCell clonesProtein expressionExpression levelsPassage numberPresent studyCellsProteomic characteristicsProteomic analysisAndrogensExpressionProgression
2007
Doxazosin-induced clusterin expression and apoptosis in prostate cancer cells
Youm YH, Yang H, Yoon YD, Kim DY, Lee C, Yoo TK. Doxazosin-induced clusterin expression and apoptosis in prostate cancer cells. Urologic Oncology Seminars And Original Investigations 2007, 25: 483-488. PMID: 18047956, DOI: 10.1016/j.urolonc.2007.02.010.Peer-Reviewed Original ResearchConceptsProstate cancer cellsAndrogen-independent human prostate cancer cellsCancer cellsHuman prostate cancer cellsTranscriptase-polymerase chain reactionNick-end labeling assayMicroM doxazosinDegree of apoptosisDNA fragmentationDoxazosin treatmentClusterin mRNA expressionPolymerase chain reactionDoxazosin-induced apoptosisClusterin expressionMRNA expressionPC3 cellsPresence of clusterinClusterin mRNAChain reactionClusterinApoptotic cellsLabeling assaysDoxazosinApoptosis