Obesity increases the production of pro-inflammatory mediators from adipose tissue T cells and compromises TCR repertoire diversity: Implications for systemic inflammation and insulin-resistance (87.32)
Youm Y, Yang H, Badanmagsar B, Gimble J, Greenway F, Mynatt R. Obesity increases the production of pro-inflammatory mediators from adipose tissue T cells and compromises TCR repertoire diversity: Implications for systemic inflammation and insulin-resistance (87.32). The Journal Of Immunology 2010, 184: 87.32-87.32. DOI: 10.4049/jimmunol.184.supp.87.32.Peer-Reviewed Original ResearchT cellsVisceral fatTCR repertoireTCR diversityAdipose depotsAdipose tissueAdipose tissue T cellsSpecific adipose depotsTCR Vβ repertoireUnique TCR repertoireEffector memory cellsObesity-associated inflammationPro-inflammatory mediatorsActivated T cell populationsPro-inflammatory cytokinesTissue T cellsT cell populationsTCR repertoire diversityProinflammatory microenvironmentSystemic inflammationObesity altersObese miceT lymphocytesObesityRepertoire diversity