Immunization and immunotherapy for cancers involving infection by a human papillomavirus in a mouse model
Li J, Sun Y, Garen A. Immunization and immunotherapy for cancers involving infection by a human papillomavirus in a mouse model. Proceedings Of The National Academy Of Sciences Of The United States Of America 2002, 99: 16232-16236. PMID: 12446839, PMCID: PMC138594, DOI: 10.1073/pnas.192581299.Peer-Reviewed Original ResearchMeSH KeywordsAdenoviridaeAnimalsAntigens, ViralCell LineCell Transformation, ViralCytotoxicity, ImmunologicDNA, ComplementaryFemaleGenes, SyntheticGenetic VectorsHumansImmunizationImmunoglobulin GImmunotherapyKidneyLung NeoplasmsLymphocyte ActivationMiceMice, Inbred C57BLNeoplasm TransplantationOncogene Proteins, ViralPapillomaviridaePapillomavirus E7 ProteinsRecombinant Fusion ProteinsSkinSpleenT-LymphocytesTransfectionViral VaccinesConceptsTC-1 tumorsTC-1 cellsHuman papillomavirusMouse modelDendritic cellsHPV 16E7 oncoproteinsTumor growthPotent cellular immune responsesCellular immune attackReplication-incompetent adenoviral vectorAdenoviral vectorCellular immune responsesHuman cancersViral-infected cellsContinuous tumor growthHPV infectionCervical cancerControl miceImmunized miceImmune attackT cellsE7 peptidesImmune responseFc receptors