IFN Regulatory Factor 8 Sensitizes Soft Tissue Sarcoma Cells to Death Receptor–Initiated Apoptosis via Repression of FLICE-like Protein Expression
Yang D, Wang S, Brooks C, Dong Z, Schoenlein PV, Kumar V, Ouyang X, Xiong H, Lahat G, Hayes-Jordan A, Lazar A, Pollock R, Lev D, Liu K. IFN Regulatory Factor 8 Sensitizes Soft Tissue Sarcoma Cells to Death Receptor–Initiated Apoptosis via Repression of FLICE-like Protein Expression. Cancer Research 2009, 69: 1080-1088. PMID: 19155307, PMCID: PMC2633427, DOI: 10.1158/0008-5472.can-08-2520.Peer-Reviewed Original ResearchAnimalsApoptosisCASP8 and FADD-Like Apoptosis Regulating ProteinCaspase 8Caspase InhibitorsCell Line, TumorEnzyme ActivationFas Ligand ProteinHumansImmunohistochemistryInterferon Regulatory FactorsMiceMitochondriaReceptors, TNF-Related Apoptosis-Inducing LigandRNA, MessengerRNA, Small InterferingSarcomaSarcoma, ExperimentalTNF-Related Apoptosis-Inducing Ligand