2022
Associations of neurotransmitters and the gut microbiome with emotional distress in mixed type of irritable bowel syndrome
Barandouzi Z, Lee J, del Carmen Rosas M, Chen J, Henderson W, Starkweather A, Cong X. Associations of neurotransmitters and the gut microbiome with emotional distress in mixed type of irritable bowel syndrome. Scientific Reports 2022, 12: 1648. PMID: 35102266, PMCID: PMC8803858, DOI: 10.1038/s41598-022-05756-0.Peer-Reviewed Original ResearchConceptsEmotional distressNeurotransmitter levelsHealthy controlsIrritable bowel syndrome groupIrritable bowel syndromeRegulation of neurotransmittersDepressive symptomsSerotonin levelsGut-brain axisEmotional symptomsHC groupPlasma neurotransmittersDistressGut microbiome profilesNeurotransmitterGut microbiomeNorepinephrine levelsBowel syndromeMicrobiome profilesPersonsNorepinephrineNested case-control studySymptomsCase-control studySerotonin
2017
Influence of Feeding Type on Gut Microbiome Development in Hospitalized Preterm Infants
Cong X, Judge M, Xu W, Diallo A, Janton S, Brownell E, Maas K, Graf J. Influence of Feeding Type on Gut Microbiome Development in Hospitalized Preterm Infants. Nursing Research 2017, 66: 123-133. PMID: 28252573, PMCID: PMC5334772, DOI: 10.1097/nnr.0000000000000208.Peer-Reviewed Original ResearchConceptsGut microbial colonizationMother's own milkPreterm infantsGut microbiomeMicrobial diversityDiversity of gut microbiomeFeeding typeGut microbial diversityGut microbiome developmentGut microbiome compositionMicrobial community patternsAbundance of EnterobacterialesIncreased microbial diversityDevelopment of preterm infantsAbundance of ClostridialesNeonatal intensive care unitBirth gestational ageStable preterm infantsRRNA genePostnatal day 0Community patternsMicrobiome compositionIntensive care unitMicrobial patternsMicrobiome development
2015
Early Life Experience and Gut Microbiome
Cong X, Henderson W, Graf J, McGrath J. Early Life Experience and Gut Microbiome. Advances In Neonatal Care 2015, 15: 314-323. PMID: 26240939, PMCID: PMC4583334, DOI: 10.1097/anc.0000000000000191.Peer-Reviewed Original ResearchConceptsGut microbiomeHigh-risk infantsStressful early life experiencesCentral nervous systemSignaling systemPreterm infantsIntestinal innate immunityPain responseBrain-gut-microbiota axisNeonatal careEarly life experiencesNeuroimmune systemMicrobial speciesNervous systemInnate immunityRegulation mechanismInfantsGutMicrobiomeTargeted interventionsRegulationModulating stressPretermState-of-the-science reviewComplex mechanisms