2022
Associations of neurotransmitters and the gut microbiome with emotional distress in mixed type of irritable bowel syndrome
Barandouzi Z, Lee J, del Carmen Rosas M, Chen J, Henderson W, Starkweather A, Cong X. Associations of neurotransmitters and the gut microbiome with emotional distress in mixed type of irritable bowel syndrome. Scientific Reports 2022, 12: 1648. PMID: 35102266, PMCID: PMC8803858, DOI: 10.1038/s41598-022-05756-0.Peer-Reviewed Original ResearchConceptsEmotional distressNeurotransmitter levelsHealthy controlsIrritable bowel syndrome groupIrritable bowel syndromeRegulation of neurotransmittersDepressive symptomsSerotonin levelsGut-brain axisEmotional symptomsHC groupPlasma neurotransmittersDistressGut microbiome profilesNeurotransmitterGut microbiomeNorepinephrine levelsBowel syndromeMicrobiome profilesPersonsNorepinephrineNested case-control studySymptomsCase-control studySerotonin
2021
Altered Gut Microbiota in Irritable Bowel Syndrome and Its Association with Food Components
Barandouzi Z, Lee J, Maas K, Starkweather A, Cong X. Altered Gut Microbiota in Irritable Bowel Syndrome and Its Association with Food Components. Journal Of Personalized Medicine 2021, 11: 35. PMID: 33429936, PMCID: PMC7827153, DOI: 10.3390/jpm11010035.Peer-Reviewed Original ResearchAlpha diversity indicesGut microbiotaIrritable bowel syndromeDiversity indexHealthy controlsHighest alpha-diversity indicesAlterations of gut microbiota compositionGut microbiota patternHigher alpha diversityGut microbiota compositionGut microbiota alterationsAltered gut microbiotaGut microbiome patternsCaffeine consumptionBowel syndromePathophysiology of irritable bowel syndromeIllumina sequencingFood frequency questionnaireAlpha diversityIrritable bowel syndrome groupIrritable bowel syndrome patientsMicrobial diversityMicrobiota compositionMicrobiota alterationsMicrobiota patterns