2019
Improving Outcomes in INTERMACS 1 Category 1 Patients with Pre-LVAD, Awake Venous-Arterial Extracorporeal Membrane Oxygenation Support
Mori M, McCloskey G, Geirsson A, Mangi AA, Yun JJ, Jacoby D, Ahmad T, Bellumkonda L, Lee F, Chen ME, Bonde P. Improving Outcomes in INTERMACS 1 Category 1 Patients with Pre-LVAD, Awake Venous-Arterial Extracorporeal Membrane Oxygenation Support. ASAIO Journal 2019, Publish Ahead of Print: &na;. PMID: 30664019, DOI: 10.1097/mat.0000000000000908.Peer-Reviewed Original ResearchConceptsCategory 1 patientsECMO supportDurable LVADECMO groupDurable left ventricular assist device implantationVenous-arterial extracorporeal membrane oxygenationLeft ventricular assist device implantationVentricular assist device implantationCox proportional hazards analysisExtracorporeal membrane oxygenation supportECMO-supported patientsPost-LVAD survivalVenous-arterial ECMOOutcomes of patientsAssist device implantationEnd-organ functionMembrane oxygenation supportProportional hazards analysisExtracorporeal membrane oxygenationRisk of deathINTERMACS scaleInteragency RegistryOxygenation supportECMO patientsUnadjusted survival
2016
Cumulative stress and autonomic dysregulation in a community sample
Lampert R, Tuit K, Hong KI, Donovan T, Lee F, Sinha R. Cumulative stress and autonomic dysregulation in a community sample. Stress 2016, 19: 269-279. PMID: 27112063, PMCID: PMC5072401, DOI: 10.1080/10253890.2016.1174847.Peer-Reviewed Original ResearchConceptsHeart rate variabilityAdverse life eventsChronic stressLife eventsPoor cardiovascular outcomesChronic stressorsCardiac autonomic functionPrimary preventive strategiesAmbulatory ECG monitoringCumulative stress scoreRegression analysisLow-frequency powerNon-invasive measureRecent life eventsCumulative stressCardiovascular outcomesAutonomic functionAutonomic dysregulationPreventive strategiesNN intervalsAutonomic statusHealthy individualsHealth behaviorsECG monitoringRate variability
2007
Effect of acetylcholinesterase inhibition with pyridostigmine on cardiac parasympathetic function in sedentary adults and trained athletes
Dewland TA, Androne AS, Lee FA, Lampert RJ, Katz SD. Effect of acetylcholinesterase inhibition with pyridostigmine on cardiac parasympathetic function in sedentary adults and trained athletes. AJP Heart And Circulatory Physiology 2007, 293: h86-h92. PMID: 17322413, DOI: 10.1152/ajpheart.01339.2006.Peer-Reviewed Original ResearchConceptsHeart rate recoveryPostexercise heart rate recoveryCardiac parasympathetic functionCardiac parasympathetic toneHeart rate variabilityRate recoveryParasympathetic toneSedentary adultsFrequency domain indicesHeart rateParasympathetic functionRate variabilityParasympathetic regulationSingle oral doseCardiac parasympathetic regulationExercise trainingCrossover trialOral doseParasympathetic pathwaysSedentary subjectsPyridostigmineHuman studiesPlaceboEfferent signalsAcetylcholinesterase inhibitors
2005
Depressed autonomic nervous system function in African Americans and individuals of lower social class: A potential mechanism of race- and class-related disparities in health outcomes
Lampert R, Ickovics J, Horwitz R, Lee F. Depressed autonomic nervous system function in African Americans and individuals of lower social class: A potential mechanism of race- and class-related disparities in health outcomes. American Heart Journal 2005, 150: 153-160. PMID: 16084163, DOI: 10.1016/j.ahj.2004.08.008.Peer-Reviewed Original Research
2004
Home continuous positive inotropic infusion as a bridge to cardiac transplantation in patients with end-stage heart failure
Upadya S, Lee FA, Saldarriaga C, Verma S, Sedrakyan A, Nystrom K, Katz SD. Home continuous positive inotropic infusion as a bridge to cardiac transplantation in patients with end-stage heart failure. The Journal Of Heart And Lung Transplantation 2004, 23: 466-472. PMID: 15063407, DOI: 10.1016/s1053-2498(03)00203-1.Peer-Reviewed Original ResearchConceptsPositive inotropic therapyInotropic therapyCardiac transplantationFunctional capacityDecreased health care costsEnd-stage heart failureImplantable cardioverter-defibrillator dischargeHome therapy patientsStatus 1B patientsInitiation of therapyStable clinical statusNumber of hospitalizationsPre-treatment baselineImplantable cardioverter defibrillatorHealth care costsActuarial survivalInotropic treatmentRenal functionConsecutive patientsHeart failureClinical statusHemodynamic monitoringHome infusionInotropic infusionUnited Network
2003
Effects of propranolol on recovery of heart rate variability following acute myocardial infarction and relation to outcome in the Beta-Blocker Heart Attack Trial
Lampert R, Ickovics JR, Viscoli CJ, Horwitz RI, Lee FA. Effects of propranolol on recovery of heart rate variability following acute myocardial infarction and relation to outcome in the Beta-Blocker Heart Attack Trial. The American Journal Of Cardiology 2003, 91: 137-142. PMID: 12521623, DOI: 10.1016/s0002-9149(02)03098-9.Peer-Reviewed Original ResearchConceptsBeta-Blocker Heart Attack TrialAcute myocardial infarctionHeart rate variabilityPlacebo-treated patientsHeart Attack TrialMyocardial infarctionEffect of propranololBeta blockersAttack TrialDepressed heart rate variabilityRate variabilityRecovery of HRVLF/HF ratioPropranolol-treated patientsWeeks of treatmentHF ratioHigh-frequency powerPropranolol therapyPropranolol treatmentSympathetic predominanceAutonomic toneParasympathetic toneSympathovagal balanceImproved outcomesSudden death
2001
Cardiac responses to insulin-induced hypoglycemia in nondiabetic and intensively treated type 1 diabetic patients
Russell R, Chyun D, Song S, Sherwin R, Tamborlane W, Lee F, Pfeifer M, Rife F, Wackers F, Young L. Cardiac responses to insulin-induced hypoglycemia in nondiabetic and intensively treated type 1 diabetic patients. AJP Endocrinology And Metabolism 2001, 281: e1029-e1036. PMID: 11595660, DOI: 10.1152/ajpendo.2001.281.5.e1029.Peer-Reviewed Original ResearchMeSH KeywordsAdultCardiac OutputCatecholaminesChemical PrecipitationDiabetes Mellitus, Type 1DiastoleEpinephrineFatty Acids, NonesterifiedFemaleGlucagonGlucose Clamp TechniqueHeartHeart RateHumansHydrocortisoneHypoglycemiaInsulinLactic AcidMaleNorepinephrinePolyethylene GlycolsStroke VolumeSystoleVentricular Function, LeftConceptsType 1 diabetic patientsInsulin-induced hypoglycemiaNondiabetic groupType 1 diabetesDiabetic subjectsEuglycemic hyperinsulinemiaDiabetic patientsNondiabetic subjectsCardiac responseLeft ventricular systolicHealthy nondiabetic subjectsEquilibrium radionuclide angiographyDiabetic groupDiastolic functionVentricular systolicCardiovascular consequencesVentricular functionBlunted increaseCardiac outputGlucagon concentrationsPlasma catecholaminesRadionuclide angiographyInsulin infusionEuglycemic conditionsHypoglycemia
2000
The feasibility of high-dose chemotherapy in breast cancer patients with impaired left ventricular function
Rose M, Lee F, Gollerkeri A, D'Andrea E, Psyrri A, Bdolah-Abram T, Burtness B. The feasibility of high-dose chemotherapy in breast cancer patients with impaired left ventricular function. Bone Marrow Transplantation 2000, 26: 133-139. PMID: 10918422, DOI: 10.1038/sj.bmt.1702449.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntineoplastic Combined Chemotherapy ProtocolsBreast NeoplasmsCombined Modality TherapyCyclophosphamideDoxorubicinFemaleFollow-Up StudiesHematopoietic Stem Cell MobilizationHematopoietic Stem Cell TransplantationHumansMiddle AgedNeutropeniaPaclitaxelStroke VolumeSurvival RateVentricular Dysfunction, LeftConceptsLeft ventricular ejection fractionHigh-dose chemotherapyBreast cancer patientsMean absolute decreaseCancer patientsAbsolute decreaseLV functionCell rescueImpaired left ventricular functionHigh-dose thiotepaImpaired LV functionHigh-dose melphalanStem cell rescueSymptomatic heart failureCourses of chemotherapyVentricular ejection fractionLeft ventricular functionSequential paclitaxelMetastatic diseaseCardiac deathCardiac symptomsEjection fractionHeart failureVentricular functionCardiac toxicity
1995
Optimal timing and indications for cholecystectomy in cardiac transplant patients
Begos D, Franco K, Baldwin J, Lee F, Revkin J, Modlin I. Optimal timing and indications for cholecystectomy in cardiac transplant patients. World Journal Of Surgery 1995, 19: 661-667. PMID: 7676717, DOI: 10.1007/bf00294752.Peer-Reviewed Original ResearchConceptsCardiac transplantSeptic complicationsTransplant patientsEnd-stage cardiac diseaseCases of cholecystectomyPostcardiac transplant patientsCardiac transplant patientsStandard management approachType of procedureAsymptomatic calculiElective cholecystectomyPosttransplant groupsPosttransplant surveillancePretransplant groupPretransplant screeningUncontrollable arrhythmiaUrgent cholecystectomyAcute cholecystitisCardiac transplantationPosttransplant patientsPretransplant patientsHeart transplantSuch patientsTransplant centersCardiac risk
1988
Peak filling rate normalized to mitral stroke volume: A new Doppler echocardiographic filling index validated by radionuclide angiographic techniques
Bowman L, Lee F, Jaffe C, Mattera J, Wackers F, Zaret B. Peak filling rate normalized to mitral stroke volume: A new Doppler echocardiographic filling index validated by radionuclide angiographic techniques. Journal Of The American College Of Cardiology 1988, 12: 937-943. PMID: 3417992, DOI: 10.1016/0735-1097(88)90458-5.Peer-Reviewed Original ResearchConceptsPeak filling rateMitral stroke volumeMean peak filling rateEnd-diastolic volumeStroke volumeFilling indexDoppler echocardiographyNormal patientsFilling velocityEarly peak filling velocityLate filling ratioEarly filling velocityDiastolic filling indexesLeft ventricular fillingTime-velocity integralPeak filling velocityRadionuclide angiographic techniquesFilling rateMitral inflowVentricular fillingMitral leafletEchocardiographic determinationMitral apparatusVelocity integralVentricular volume