2016
Cumulative stress and autonomic dysregulation in a community sample
Lampert R, Tuit K, Hong KI, Donovan T, Lee F, Sinha R. Cumulative stress and autonomic dysregulation in a community sample. Stress 2016, 19: 269-279. PMID: 27112063, PMCID: PMC5072401, DOI: 10.1080/10253890.2016.1174847.Peer-Reviewed Original ResearchConceptsHeart rate variabilityAdverse life eventsChronic stressLife eventsPoor cardiovascular outcomesChronic stressorsCardiac autonomic functionPrimary preventive strategiesAmbulatory ECG monitoringCumulative stress scoreRegression analysisLow-frequency powerNon-invasive measureRecent life eventsCumulative stressCardiovascular outcomesAutonomic functionAutonomic dysregulationPreventive strategiesNN intervalsAutonomic statusHealthy individualsHealth behaviorsECG monitoringRate variability
2010
Common Genes Contribute to Depressive Symptoms and Heart Rate Variability: The Twins Heart Study
Su S, Lampert R, Lee F, Bremner JD, Snieder H, Jones L, Murrah NV, Goldberg J, Vaccarino V. Common Genes Contribute to Depressive Symptoms and Heart Rate Variability: The Twins Heart Study. Twin Research And Human Genetics 2010, 13: 1-9. PMID: 20158303, PMCID: PMC2905576, DOI: 10.1375/twin.13.1.1.Peer-Reviewed Original ResearchConceptsHeart rate variabilityCoronary artery diseaseDepressive symptomsHRV indicesReduced heart rate variabilityRate variabilityElectrocardiographic Holter recordingsMeasurements of HRVBeck Depression Inventory-IICurrent depressive symptomsSignificant inverse correlationVietnam Era Twin RegistryFrequency domain variablesBivariate genetic modelingCommon neurobiological dysfunctionArtery diseaseAutonomic dysregulationHolter recordingsHeart StudyMiddle-aged male twinsHRV frequencySymptomsCommon genetic componentInventory-IIHigh frequency
2008
Decreased heart rate variability is associated with higher levels of inflammation in middle-aged men
Lampert R, Bremner JD, Su S, Miller A, Lee F, Cheema F, Goldberg J, Vaccarino V. Decreased heart rate variability is associated with higher levels of inflammation in middle-aged men. American Heart Journal 2008, 156: 759.e1-759.e7. PMID: 18926158, PMCID: PMC2587932, DOI: 10.1016/j.ahj.2008.07.009.Peer-Reviewed Original ResearchConceptsC-reactive proteinCoronary artery diseaseBody mass indexHeart rate variabilityTraditional risk factorsInterleukin-6Risk factorsAutonomic functionPhysical activityDevelopment of CADSymptomatic coronary artery diseaseTraditional CAD risk factorsHigh-density lipoprotein cholesterolRate variabilityGraded inverse relationshipCAD risk factorsMiddle-aged menHigh-density lipoproteinAmbulatory electrocardiogram monitoringHigh-frequency powerAutonomic dysfunctionLipoprotein cholesterolArtery diseaseMass indexAutonomic dysregulation