2000
Temporal Events Underlying Arterial Remodeling After Chronic Flow Reduction in Mice
Rudic R, Bucci M, Fulton D, Segal S, Sessa W. Temporal Events Underlying Arterial Remodeling After Chronic Flow Reduction in Mice. Circulation Research 2000, 86: 1160-1166. PMID: 10850968, DOI: 10.1161/01.res.86.11.1160.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCarotid Artery, CommonCell DeathDrug CombinationsIn Vitro TechniquesMaleMiceMice, Inbred C57BLMuscle, Smooth, VascularNitric OxideNitric Oxide SynthaseNitric Oxide Synthase Type IINitric Oxide Synthase Type IIIRegional Blood FlowTime FactorsTunica MediaVasodilator AgentsVasomotor SystemConceptsLeft common carotid arteryRight common carotid arteryCommon carotid arteryCarotid arteryBlood flowLeft external carotid arteryEndothelial NO synthase (eNOS) functionEndothelial NO synthase (eNOS) mRNAExternal carotid arteryNO synthase mRNANitrovasodilator sodium nitroprussideAcute ligationEndothelial dysfunctionArterial remodelingControl arteriesVascular remodelingAdult miceSodium nitroprussideDay 7Structural remodelingArteryLuminal remodelingMarked reductionProtein levelsMice
1999
Molecular control of nitric oxide synthases in the cardiovascular system
Papapetropoulos A, Rudic R, Sessa W. Molecular control of nitric oxide synthases in the cardiovascular system. Cardiovascular Research 1999, 43: 509-520. PMID: 10690323, DOI: 10.1016/s0008-6363(99)00161-3.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBlood PressureCardiovascular DiseasesCardiovascular SystemCentral Nervous SystemGene Expression RegulationHomeostasisHumansImmune SystemMiceMice, KnockoutNeovascularization, PathologicNitric OxideNitric Oxide SynthaseNitric Oxide Synthase Type INitric Oxide Synthase Type IINitric Oxide Synthase Type IIIRatsVasomotor SystemA vascular bed–specific pathway regulates cardiac expression of endothelial nitric oxide synthase
Guillot P, Guan J, Liu L, Kuivenhoven J, Rosenberg R, Sessa W, Aird W. A vascular bed–specific pathway regulates cardiac expression of endothelial nitric oxide synthase. Journal Of Clinical Investigation 1999, 103: 799-805. PMID: 10079100, PMCID: PMC408151, DOI: 10.1172/jci6017.Peer-Reviewed Original ResearchConceptsEndothelial nitric oxide synthase geneEndothelial nitric oxide synthaseMurine endothelial progenitor cellsGrowth factor antibodyNitric oxide synthase geneNitric oxide synthaseEndothelial progenitor cellsOxide synthase geneFactor antibodyOxide synthaseVascular bedResponse elementCardiac expressionTransgenic micePDGF-ABCardiac endotheliumEno expressionCardiac myocytesSkeletal muscleProgenitor cellsSkeletal myocytesEndotheliumMiceBrainBeta-galactosidase activity