2016
Initial development of patient-reported instrument assessing harm, efficacy, and misuse of long-term opioid therapy
Becker WC, Fiellin DA, Black AC, Kostovich CT, Kerns RD, Fraenkel L. Initial development of patient-reported instrument assessing harm, efficacy, and misuse of long-term opioid therapy. The Journal Of Rehabilitation Research And Development 2016, 53: 127-136. PMID: 27006339, PMCID: PMC4806533, DOI: 10.1682/jrrd.2014.11.0285.Peer-Reviewed Original ResearchConceptsLong-term opioid therapyPatient-reported instrumentOpioid therapyFurther item reductionIneffective medicationsClinical outcomesPrimary careFrequent reassessmentPatient comprehensionItem reductionGold standardEfficacyTherapyInterdisciplinary teamLevel checksCognitive interviewsMisuseHarmMedicationsPatients
2014
Buprenorphine/Naloxone Dose and Pain Intensity Among Individuals Initiating Treatment for Opioid Use Disorder
Becker WC, Ganoczy D, Fiellin DA, Bohnert AS. Buprenorphine/Naloxone Dose and Pain Intensity Among Individuals Initiating Treatment for Opioid Use Disorder. Journal Of Substance Use And Addiction Treatment 2014, 48: 128-131. PMID: 25312475, DOI: 10.1016/j.jsat.2014.09.007.Peer-Reviewed Original ResearchConceptsOpioid use disorderNumerical rating scoreBUP/NXPain intensityUse disordersPrimary outcomeBuprenorphine/naloxone doseDecreased pain intensityFull agonist opioidsImproved pain intensityBuprenorphine/naloxoneSubset of patientsSubstance use comorbiditiesChronic pain diagnosesPartial agonist propertiesEligible patientsNX treatmentAgonist opioidsPain levelsNaloxone doseComorbid painMultivariable analysisMaintenance treatmentMean ageClinical correlates
2010
The Safety of Opioid Analgesics in the Elderly: New Data Raise New Concerns: Comment on “The Comparative Safety of Opioids for Nonmalignant Pain in Older Adults”
Becker WC, O'Connor PG. The Safety of Opioid Analgesics in the Elderly: New Data Raise New Concerns: Comment on “The Comparative Safety of Opioids for Nonmalignant Pain in Older Adults”. JAMA Internal Medicine 2010, 170: 1986-1988. PMID: 21149755, DOI: 10.1001/archinternmed.2010.443.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnalgesics, OpioidAnti-Inflammatory Agents, Non-SteroidalCardiovascular DiseasesComorbidityContraindicationsCyclooxygenase 2 InhibitorsDrug UtilizationFemaleFractures, BoneGastrointestinal HemorrhageHumansMaleMedicareObservationPainPain MeasurementResearch DesignTherapeutic EquivalencyUnited States