2023
The effects of flow settings during high-flow nasal cannula support for adult subjects: a systematic review
Li J, Albuainain F, Tan W, Scott J, Roca O, Mauri T. The effects of flow settings during high-flow nasal cannula support for adult subjects: a systematic review. Critical Care 2023, 27: 78. PMID: 36855198, PMCID: PMC9974062, DOI: 10.1186/s13054-023-04361-5.Peer-Reviewed Original ResearchConceptsHigh-flow nasal cannulaHigh-flow nasal cannula treatmentIn vivo studiesPatient's peak inspiratory flowHigh-flow nasal cannula supportFraction of inspired oxygenPositive end-expiratory pressurePeak inspiratory flowSystematic reviewEnd-expiratory pressureDead space washoutNon-dependent lung regionsIn vitro studiesRisk of biasROX indexNasal cannulaClinical findingsImprove oxygenationPediatric populationPatient discomfortAlveolar overdistentionInspiratory flowWeb of SciencePatient comfortPatients
2022
Effectiveness of the use of a high-flow nasal cannula to treat COVID-19 patients and risk factors for failure: a meta-analysis
Xu D, Dai B, Tan W, Zhao H, Wang W, Kang J. Effectiveness of the use of a high-flow nasal cannula to treat COVID-19 patients and risk factors for failure: a meta-analysis. Therapeutic Advances In Respiratory Disease 2022, 16: 17534666221091931. PMID: 35467449, PMCID: PMC9047804, DOI: 10.1177/17534666221091931.Peer-Reviewed Original ResearchConceptsHigh-flow nasal cannulaInitiation of high-flow nasal cannulaHigh-flow nasal cannula failureSequential Organ Failure AssessmentRegister of Randomized Controlled TrialsCOVID-19 patientsBody mass indexFailure groupROX indexRisk factorsHigher heart rateWhite blood cellsNasal cannulaChronic Health Evaluation (APACHE) II scoreEfficacy of high-flow nasal cannulaHeart rateDuration of HFNCOdds ratioCochrane Central Register of Randomized Controlled TrialsRisk of HFNC failureHigher white blood cellWhite blood cell countLower ROX indexOrgan Failure AssessmentPooled odds ratio