2011
Golgi during Development
Zhong W. Golgi during Development. Cold Spring Harbor Perspectives In Biology 2011, 3: a005363. PMID: 21768608, PMCID: PMC3181030, DOI: 10.1101/cshperspect.a005363.Peer-Reviewed Original ResearchConceptsPlasma membrane componentsSecretory traffickingSecretory pathwayProcessing proteinsCellular differentiationDevelopmental pathwaysProtein cleavageMembrane componentsGolgiAspects of developmentSpatial organizationMajor compartmentsPathwayFinal destinationInvertebratesVertebratesMorphogenesisOrganellesTraffickingGlycosylationProteinSpecific effectsDifferentiationCompartmentsCleavage
2007
The Mammalian Golgi Regulates Numb Signaling in Asymmetric Cell Division by Releasing ACBD3 during Mitosis
Zhou Y, Atkins JB, Rompani SB, Bancescu DL, Petersen PH, Tang H, Zou K, Stewart SB, Zhong W. The Mammalian Golgi Regulates Numb Signaling in Asymmetric Cell Division by Releasing ACBD3 during Mitosis. Cell 2007, 129: 163-178. PMID: 17418793, DOI: 10.1016/j.cell.2007.02.037.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Proteins, Signal TransducingAnimalsAnimals, Genetically ModifiedCell DivisionCell LineageCytosolDrosophilaEmbryo, MammalianEmbryo, NonmammalianEmbryonic DevelopmentGolgi ApparatusMembrane ProteinsMiceMitosisNerve Tissue ProteinsNeuronsPhenotypeProtein Structure, TertiaryReceptors, GABA-ASignal TransductionStem CellsConceptsCell fate specificationNumb proteinDaughter cellsGolgi fragmentationCell cycleMammalian neural progenitor cellsAsymmetric cell divisionProgenitor cell cycleProgenitor cellsCell cycle progressionNeural progenitor cellsMammalian GolgiCell fateCell divisionNeuronal fateACBD3Golgi apparatusSubcellular distributionNeuronal differentiationPhenotypic similarityNumbMitosisNeuron productionProteinCells
2005
The Notch Regulator Numb Links the Notch and TCR Signaling Pathways
Anderson AC, Kitchens EA, Chan SW, St. Hill C, Jan YN, Zhong W, Robey EA. The Notch Regulator Numb Links the Notch and TCR Signaling Pathways. The Journal Of Immunology 2005, 174: 890-897. PMID: 15634911, DOI: 10.4049/jimmunol.174.2.890.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigen-Presenting CellsCell DifferentiationCells, CulturedGene DeletionIntracellular Signaling Peptides and ProteinsMembrane ProteinsMiceMice, TransgenicNerve Tissue ProteinsReceptor, Notch1Receptors, Antigen, T-CellReceptors, Cell SurfaceSignal TransductionT-LymphocytesThymus GlandTranscription FactorsConceptsT cell developmentTCR signaling pathwaysCell developmentSignaling pathwaysAbsence of NumbT cell-APC interactionsInhibitor of NotchProtein NumbImportant adapterRelated proteinsNumbAPC contactMature T cellsTCR signalsCell membraneT cell activationPhysical interactionPathwayCell activationNotchImportant roleNumblikeProteinMutationsCoclusters
1999
DLX‐1, DLX‐2, and DLX‐5 expression define distinct stages of basal forebrain differentiation
Eisenstat D, Liu J, Mione M, Zhong W, Yu G, Anderson S, Ghattas I, Puelles L, Rubenstein J. DLX‐1, DLX‐2, and DLX‐5 expression define distinct stages of basal forebrain differentiation. The Journal Of Comparative Neurology 1999, 414: 217-237. PMID: 10516593, DOI: 10.1002/(sici)1096-9861(19991115)414:2<217::aid-cne6>3.0.co;2-i.Peer-Reviewed Original ResearchMeSH Keywords3T3 CellsAnimalsAntibody SpecificityBasal GangliaCell DifferentiationCell NucleusCerebral VentriclesCytoplasmGene Expression Regulation, DevelopmentalHomeodomain ProteinsIn Situ HybridizationIsomerismMiceMitosisMutagenesisNeuronsProsencephalonRecombinant ProteinsRNA, MessengerS PhaseTranscription FactorsConceptsDlx-2Dlx-1Dlx-5Dlx genesDlx-5 expressionEmbryonic day 10.5Ventricular zoneDlx proteinsDlx familyM phase cellsCraniofacial morphogenesisHomeobox genesSingle mutantsDaughter cellsDay 10.5GenesForebrain differentiationProteinSame cellsMouse forebrainMild phenotypeCellsDifferentiationExpressionDistinct stages