The expression pattern of a Drosophila homolog to the mouse transcription factor HNF‐4 suggests a determinative role in gut formation.
Zhong W, Sladek F, Darnell J. The expression pattern of a Drosophila homolog to the mouse transcription factor HNF‐4 suggests a determinative role in gut formation. The EMBO Journal 1993, 12: 537-544. PMID: 8440243, PMCID: PMC413236, DOI: 10.1002/j.1460-2075.1993.tb05685.x.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsChromosome DeletionChromosome MappingDNA-Binding ProteinsDrosophilaGene ExpressionHepatocyte Nuclear Factor 4In Situ HybridizationIntestinal MucosaIntestinesKidneyLiverMiceMolecular Sequence DataPhenotypePhosphoproteinsRNA, MessengerSequence Homology, Amino AcidTranscription FactorsConceptsDNA-binding domainDrosophila genesGut formationHNF-4Binding domainIdentical DNA binding domainsZinc finger DNA-binding domainHepatocyte nuclear factor 3Transcription factor HNF-4Amino acidsGroup of genesLiver-specific gene expressionDrosophila homologDrosophila embryoDrosophila mutantsMouse genesHNF-3Cross-hybridizationLate embryogenesisChromosomal deletionsDrosophilaFat bodyGene expressionExpression patternsGenes