Does N-Terminal Pro-B-Type Natriuretic Peptide Improve the Risk Stratification of Emergency Department Patients With Syncope?
Thiruganasambandamoorthy V, McRae AD, Rowe BH, Sivilotti MLA, Mukarram M, Nemnom MJ, Booth RA, Calder LA, Stiell IG, Wells GA, Cheng W, Taljaard M. Does N-Terminal Pro-B-Type Natriuretic Peptide Improve the Risk Stratification of Emergency Department Patients With Syncope? Annals Of Internal Medicine 2020, 172: 648-655. PMID: 32340039, DOI: 10.7326/m19-3515.Peer-Reviewed Original ResearchConceptsCanadian Syncope Risk ScoreSerious adverse eventsPro-B-type natriuretic peptideSerum NT-proBNP concentrationNT-proBNP concentrationsNT-proBNPNatriuretic peptideED patientsN-terminal pro-B-type natriuretic peptideTerminal pro-B-type natriuretic peptidePhysicians Services Incorporated FoundationIndex ED visitNT-proBNP valuesAdult ED patientsProspective cohort studySerum NT-proBNPEmergency department patientsNet reclassification indexHeterogeneity of outcomesAdjudication of outcomesNoncardiac eventsED dispositionAdverse eventsCohort studyComposite outcomeAccuracy of the Multinational Association of Supportive Care in Cancer (MASCC) and Clinical Index of Stable Febrile Neutropenia (CISNE) scores for predicting serious complications in adult patients with febrile neutropenia: A systematic review and meta-analysis
Zheng B, Toarta C, Cheng W, Taljaard M, Reaume N, Perry JJ. Accuracy of the Multinational Association of Supportive Care in Cancer (MASCC) and Clinical Index of Stable Febrile Neutropenia (CISNE) scores for predicting serious complications in adult patients with febrile neutropenia: A systematic review and meta-analysis. Critical Reviews In Oncology/Hematology 2020, 149: 102922. PMID: 32244162, DOI: 10.1016/j.critrevonc.2020.102922.Peer-Reviewed Original ResearchConceptsMultinational AssociationSupportive careSerious complicationsClinical indicesPooled sensitivitySystematic reviewFebrile neutropenia patientsCISNE scoreMASCC scoreFebrile neutropeniaAcute settingAdult patientsCochrane DatabaseNeutropenia patientsPatientsComplicationsScoresCancerCareAssociationSpecificityNeutropeniaMASCCEMBASEReviewPre-arrest and intra-arrest prognostic factors associated with survival after in-hospital cardiac arrest: systematic review and meta-analysis
Fernando SM, Tran A, Cheng W, Rochwerg B, Taljaard M, Vaillancourt C, Rowan KM, Harrison DA, Nolan JP, Kyeremanteng K, McIsaac DI, Guyatt GH, Perry JJ. Pre-arrest and intra-arrest prognostic factors associated with survival after in-hospital cardiac arrest: systematic review and meta-analysis. The BMJ 2019, 367: l6373. PMID: 31801749, PMCID: PMC6891802, DOI: 10.1136/bmj.l6373.Peer-Reviewed Original ResearchMeSH KeywordsAdultFemaleHeart ArrestHospital MortalityHumansMaleOdds RatioPrognosisRisk AssessmentRisk FactorsSex FactorsUnited KingdomConceptsHospital cardiac arrestCardiac arrestPrognostic factorsSystematic reviewReduced oddsPrimary analysisInitial shockable rhythmIntra-arrest factorsPre-arrest factorsHigh-certainty evidenceChronic kidney diseaseDuration of resuscitationRisk of biasEnglish-language studiesWeb of ScienceActive malignancyCertainty evidenceCohort studyGRADE approachOdds of survivalCochrane DatabaseMale sexKidney diseaseShockable rhythmRelevant confoundersPrognostic Accuracy of the HEART Score for Prediction of Major Adverse Cardiac Events in Patients Presenting With Chest Pain: A Systematic Review and Meta‐analysis
Fernando SM, Tran A, Cheng W, Rochwerg B, Taljaard M, Thiruganasambandamoorthy V, Kyeremanteng K, Perry JJ. Prognostic Accuracy of the HEART Score for Prediction of Major Adverse Cardiac Events in Patients Presenting With Chest Pain: A Systematic Review and Meta‐analysis. Academic Emergency Medicine 2018, 26: 140-151. PMID: 30375097, DOI: 10.1111/acem.13649.Peer-Reviewed Original ResearchConceptsMajor adverse cardiac eventsPrediction of MACEAdverse cardiac eventsHEART scorePrediction of mortalityChest painMyocardial infarctionPrognostic accuracyCardiac eventsTIMI scoreLow-risk thresholdSystematic reviewPrediction of MIMyocardial Infarction (TIMI) scoreAdult ED patientsChest pain patientsShort-term incidenceClinical decision instrumentWeb of ScienceAdult patientsPain patientsED patientsRisk stratificationCochrane DatabasePatient population