Diagnosis of elevated intracranial pressure in critically ill adults: systematic review and meta-analysis
Fernando SM, Tran A, Cheng W, Rochwerg B, Taljaard M, Kyeremanteng K, English SW, Sekhon MS, Griesdale DEG, Dowlatshahi D, McCredie VA, Wijdicks EFM, Almenawer SA, Inaba K, Rajajee V, Perry JJ. Diagnosis of elevated intracranial pressure in critically ill adults: systematic review and meta-analysis. The BMJ 2019, 366: l4225. PMID: 31340932, PMCID: PMC6651068, DOI: 10.1136/bmj.l4225.Peer-Reviewed Original ResearchConceptsElevated intracranial pressureOptic nerve sheath diameterIntracranial pressureNon-invasive testsMidline shiftIll patientsPhysical examinationSystematic reviewPhysical examination signsDoppler pulsatility indexGlasgow Coma ScaleNerve sheath diameterInvasive ICP monitoringPhysical examination featuresPatient-level dataDiagnostic Accuracy Studies toolTranscranial Doppler pulsatility indexEnglish-language studiesHierarchical summary receiverExamination signsComa ScaleCT findingsIll adultsPulsatility indexBasal cisterns