External validation of ELASTIC NET regression models including newborn metabolomic markers for postnatal gestational age estimation in East and South-East Asian infants
Hawken S, Murphy M, Ducharme R, Bota A, Wilson L, Cheng W, Tumulak M, Alcausin M, Reyes M, Qiu W, Potter B, Little J, Walker M, Zhang L, Padilla C, Chakraborty P, Wilson K. External validation of ELASTIC NET regression models including newborn metabolomic markers for postnatal gestational age estimation in East and South-East Asian infants. Gates Open Research 2020, 4: 164. DOI: 10.12688/gatesopenres.13131.1.Peer-Reviewed Original ResearchCohort of infantsBirth weightMetabolomic markersLow-resource settingsResource settingsGrowth-restricted infantsNewborn metabolic profilesHeel-prick blood sampleRetrospective database studyNewborn screening programsGestational age estimationAsian infantsScreening programChinese cohortClinical utilityDatabase studyBlood samplesInfantsPostnatal gestational age estimationCohortUltrasound valuesMetabolic profileInternal validationMetabolomics modelBirth estimates