2023
Test Characteristics of Emergency Medicine-Performed Point-of-Care Ultrasound for the Diagnosis of Acute Cholecystitis: A Systematic Review and Meta-analysis
Wilson S, Thavanathan R, Cheng W, Stuart J, Kim D, Glen P, Duigenan S, Shorr R, Woo M, Perry J. Test Characteristics of Emergency Medicine-Performed Point-of-Care Ultrasound for the Diagnosis of Acute Cholecystitis: A Systematic Review and Meta-analysis. Annals Of Emergency Medicine 2023, 83: 235-246. PMID: 37855790, DOI: 10.1016/j.annemergmed.2023.09.005.Peer-Reviewed Original ResearchEmergency physician-performed pointAcute cholecystitisCare ultrasoundSystematic reviewFinal diagnosisDiagnostic accuracyEarly surgical managementAcute abdominal painMeta-Analyses (PRISMA) guidelinesPreferred Reporting ItemsFull-text reviewTitles/abstractsReference standardPositive likelihood ratioHierarchical summary receiverNegative likelihood ratioAbdominal painLikelihood ratioClinical suspicionHospital admissionDefinitive managementSurgical managementEmergency departmentBias assessmentEligible studies
2021
Clinical and pharmacokinetic/dynamic outcomes of prolonged infusions of beta-lactam antimicrobials: An overview of systematic reviews
Thabet P, Joshi A, MacDonald E, Hutton B, Cheng W, Stevens A, Kanji S. Clinical and pharmacokinetic/dynamic outcomes of prolonged infusions of beta-lactam antimicrobials: An overview of systematic reviews. PLOS ONE 2021, 16: e0244966. PMID: 33481817, PMCID: PMC7822342, DOI: 10.1371/journal.pone.0244966.Peer-Reviewed Original ResearchConceptsBeta-lactam antimicrobialsClinical cureSystematic reviewProlonged infusionBeta-lactam infusionDefinitive systematic reviewLess sick patientsLength of stayCurrent systematic reviewOverview of reviewsEmergence of resistanceBeta-lactam antibioticsSubsequent systematic reviewsAdverse eventsMicrobiological cureHospitalized patientsIll patientsClinical outcomesIntermittent infusionTreatment failureDATA EXTRACTIONCochrane LibraryMethodologic qualityPROSPERO registryBias assessment