1988
The treatment of indolent lymphomas: watchful waiting v aggressive combined modality treatment.
Young R, Longo D, Glatstein E, Ihde D, Jaffe E, DeVita V. The treatment of indolent lymphomas: watchful waiting v aggressive combined modality treatment. Seminars In Hematology 1988, 25: 11-6. PMID: 2456618.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic Combined Chemotherapy ProtocolsCombined Modality TherapyCyclophosphamideDoxorubicinEtoposideEvaluation Studies as TopicHumansLeucovorinLeukemiaLeukemia, Radiation-InducedLymph NodesLymphoma, Non-HodgkinMechlorethamineMethotrexateNeoplasms, Multiple PrimaryNeoplasms, Radiation-InducedPalliative CarePrednisoneProcarbazineRandom AllocationVincristineConceptsAdvanced indolent lymphomaLimited radiation therapyTotal nodal irradiationIndolent lymphomaRadiation therapyModality treatmentInitial treatmentAggressive combined modality therapyCombined modality therapyEvaluable patientsInduction therapyInitial therapyNodal irradiationFirst remissionInitial remissionFrequent relapsesMedian durationModality therapySystemic therapyCombination chemotherapyMedian timeHistologic progressionLonger survivalPatient's diseasePatients
1984
NIH conference. T-cell lymphoproliferative syndrome associated with human T-cell leukemia/lymphoma virus.
Broder S, Bunn P, Jaffe E, Blattner W, Gallo R, Wong-Staal F, Waldmann T, DeVita V. NIH conference. T-cell lymphoproliferative syndrome associated with human T-cell leukemia/lymphoma virus. Annals Of Internal Medicine 1984, 100: 543-57. PMID: 6322632, DOI: 10.7326/0003-4819-100-4-543.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeAdultAnimalsCell Transformation, NeoplasticCell Transformation, ViralDeltaretrovirusFemaleHumansLeukemia, LymphoidLymph NodesLymphomaLymphoproliferative DisordersMaleMiddle AgedNeoplastic Cells, CirculatingPhenotypeSyndromeT-LymphocytesTumor Virus InfectionsConceptsHuman T-cell leukemia/lymphoma virusAdult T-cell leukemia/lymphomaT-cell leukemia/lymphomaT-cell tropicLeukemia/lymphomaImmunologic featuresOpportunistic infectionsLymphoproliferative disordersLymphoproliferative syndromeMolecular biologicRNA tumor virusesTumor virusVirusClasses of retrovirusesMajor advancesRetrovirusesHypercalcemia
1982
Undifferentiated non‐Hodgkin'S lymphomas (Burkitt's and non‐Burkitt's types). The relevance of making this histologic distinction
Miliauskas J, Berard C, Young R, Garvin A, Edwards B, Devita V. Undifferentiated non‐Hodgkin'S lymphomas (Burkitt's and non‐Burkitt's types). The relevance of making this histologic distinction. Cancer 1982, 50: 2115-2121. PMID: 7127252, DOI: 10.1002/1097-0142(19821115)50:10<2115::aid-cncr2820501024>3.0.co;2-9.Peer-Reviewed Original ResearchConceptsBurkitt's lymphomaMedian ageStage IVPrimary siteHistologic distinctionIntra-abdominal involvementFive-year survivalNational Cancer InstituteMedian survivalBurkitt's typeRetrospective studyHodgkin's lymphomaPatient populationLonger survivalCancer InstituteLymphomaPatientsSurvivalDiseaseMonthsAgePresentationYearsCasesHistologic progression in non-Hodgkin's lymphoma.
Hubbard S, Chabner B, DeVita V, Simon R, Berard C, Jones R, Garvin A, Canellos G, Osborne C, Young R. Histologic progression in non-Hodgkin's lymphoma. Blood 1982, 59: 258-64. PMID: 7034812, DOI: 10.1182/blood.v59.2.258.bloodjournal592258.Peer-Reviewed Original Research
1981
Natural history of malignant lymphomas with divergent histologies at staging evaluation
Fisher R, Jones R, Devita V, Simon R, Garvin A, Berard C, Young R. Natural history of malignant lymphomas with divergent histologies at staging evaluation. Cancer 1981, 47: 2022-2025. PMID: 7226096, DOI: 10.1002/1097-0142(19810415)47:8<2022::aid-cncr2820470820>3.0.co;2-v.Peer-Reviewed Original ResearchConceptsDifferent histologic diagnosesHistologic diagnosisNatural historyStaging evaluationMalignant lymphomaDiffuse patternNodular patternTissue sitesComplete response rateInitial staging evaluationNational Cancer InstituteMultiple tissue sitesMedian survivalMedical recordsCancer InstituteDivergent histologyPatientsBiopsyResponse ratePlanning treatmentUnique natural historyDiagnosisMonthsLymphomaTreatment
1980
Non-Hodgkin's lymphomas in leukemic phase: Clinicopathologic correlations
Come S, Jaffe E, Andersen J, Mann R, Johnson B, DeVita V, Young R. Non-Hodgkin's lymphomas in leukemic phase: Clinicopathologic correlations. The American Journal Of Medicine 1980, 69: 667-674. PMID: 7001897, DOI: 10.1016/0002-9343(80)90416-7.Peer-Reviewed Original ResearchConceptsPeripheral blood involvementBlood involvementHistologic subtypeLeukemic phaseAdult lymphoblastic lymphomaDiffuse large cell lymphomaNon-Hodgkin lymphomaLarge cell lymphomaHomogeneous clinical pictureTypes of NHLLymphoblastic lymphomaRappaport classificationClinical pictureClinicopathologic entityHodgkin's lymphomaNodular lymphomaUnresponsive diseaseClinicopathologic correlationLymphocytic lymphomaClinical subtypesLeukemic conversionCell lymphomaCytologic featuresHigh riskPredominant cellsThe evolution of primary multimodality treatment in resectable breast cancer
Henney J, Devita V. The evolution of primary multimodality treatment in resectable breast cancer. Cancer 1980, 46: 999-1008. PMID: 6994877, DOI: 10.1002/1097-0142(19800815)46:4+<999::aid-cncr2820461325>3.0.co;2-e.Peer-Reviewed Original ResearchConceptsDisease-free intervalPremenopausal womenClinical trialsBreast cancerProspective randomized clinical trialsStage II breast cancerAdjuvant therapy studiesResectable breast cancerRandomized clinical trialsNational Cancer InstitutePositive resultsPostmenopausal womenMultimodality treatmentPostoperative periodPrognostic factorsNational mortalityClinical dataEstrogen receptorDrug doseCancer InstituteStage IClinical researchPatientsTherapy studiesTrialsNodular histiocytic lymphoma: an aggressive nodular lymphoma with potential for prolonged disease-free survival.
Osborne C, Norton L, Young R, Garvin A, Simon R, Berard C, Hubbard S, DeVita V. Nodular histiocytic lymphoma: an aggressive nodular lymphoma with potential for prolonged disease-free survival. Blood 1980, 56: 98-103. PMID: 6992889, DOI: 10.1182/blood.v56.1.98.bloodjournal56198.Peer-Reviewed Original ResearchMeSH KeywordsHumansLymph NodesLymphomaLymphoma, Large B-Cell, DiffuseNeoplasm StagingRetrospective StudiesTime FactorsConceptsNodular histiocytic lymphomasDiffuse histiocytic lymphomaHistiocytic lymphomaNodular lymphomaPathological stageProlonged disease-free survivalNatural historyLymph node biopsyNon-Hodgkin's lymphomaDisease-free survivalSubtypes of lymphomaTreated with cyclophosphamideLymph node examinationLymph node histologyGroup of patientsLong-term survivorsCombination chemotherapyNode biopsyNode examinationLiver involvementNode histologyLymphomaTherapeutic strategiesPatientsLymph
1978
Patterns of relapse in advanced Hodgkin's disease treated with combination chemotherapy
Young R, Canellos G, Chabner B, Hubbard S, Devita V. Patterns of relapse in advanced Hodgkin's disease treated with combination chemotherapy. Cancer 1978, 42: 1001-1007. PMID: 688174, DOI: 10.1002/1097-0142(197808)42:2+<1001::aid-cncr2820420723>3.0.co;2-z.Peer-Reviewed Original ResearchConceptsPatterns of relapseAdvanced Hodgkin's diseaseComplete remissionCombination chemotherapyHodgkin's diseasePrevious diseaseNodal sitesNodular sclerosis histologyProphylactic radiation therapyLeft supraclavicular areaSite of diseaseNodal diseaseSystemic symptomsSupraclavicular areaRadiation therapyRelapse increasesNodal areasPatientsRelapseDiseaseRemissionChemotherapyHistologyTherapy
1977
The treatment of Hodgkin's disease
Young R, Anderson T, DeVita V. The treatment of Hodgkin's disease. Current Problems In Cancer 1977, 1: 1-29. PMID: 66119, DOI: 10.1016/s0147-0272(77)80009-3.Peer-Reviewed Original ResearchMeSH KeywordsAdultBleomycinBone MarrowChildClinical Trials as TopicDrug Therapy, CombinationFemaleHodgkin DiseaseHumansLaparoscopyLaparotomyLiverLymph NodesMaleMechlorethamineNational Institutes of Health (U.S.)Neoplasms, Multiple PrimaryPrednisoneProcarbazineRadiotherapy, High-EnergySpleenSplenectomyUnited StatesVincristine
1976
Pathological staging of 100 consecutive untreated patients with non‐Hodgkin's lymphomas. Extramedullary sites of disease
Lotz M, Chabner B, Devita V, Johnson R, Berard C. Pathological staging of 100 consecutive untreated patients with non‐Hodgkin's lymphomas. Extramedullary sites of disease. Cancer 1976, 37: 266-270. PMID: 1247961, DOI: 10.1002/1097-0142(197601)37:1<266::aid-cncr2820370136>3.0.co;2-z.Peer-Reviewed Original ResearchConceptsPathological stagingHodgkin's lymphomaNodular lymphomaHepatic biopsyDiffuse lymphomaFirst positive biopsyPercutaneous hepatic biopsyConsecutive untreated patientsBone marrow needle biopsyNegative spleensAbdominal involvementExploratory laparotomyUntreated patientsHepatic involvementWedge biopsyHistologic typeOverall incidenceRappaport classificationAbdominal diseasePositive biopsiesExtramedullary sitesNeedle biopsyUntreated casesPatientsBiopsy
1975
Patterns of involvement with malignant lymphoma and implications for treatment decision making.
Johnson R, DeVita V, Kun L, Chabner B, Chretien P, Berard C, Johnson S. Patterns of involvement with malignant lymphoma and implications for treatment decision making. British Journal Of Cancer. Supplement 1975, 2: 237-41. PMID: 1182071, PMCID: PMC2149575.Peer-Reviewed Original ResearchConceptsMalignant lymphomaTreatment decisionsPresentation of lymphomaPrimary extranodal lymphomaMajority of patientsUntreated malignant lymphomaPattern of involvementMajority of casesLymphatic irradiationProspective stagingSurgical stagingExtranodal lymphomaExtranodal sitesHaematogenous spreadSystemic treatmentClinical courseConsecutive patientsLymph nodesDisease extentHodgkin's diseaseDisseminated involvementAppropriate treatmentLymphatic extensionPrimary manifestationHigh doseNon‐Hodgkin's lymphoma: Patterns of relapse from complete remission after combination chemotherapy
Schein P, Chabner B, Canellos G, Young R, Devita V. Non‐Hodgkin's lymphoma: Patterns of relapse from complete remission after combination chemotherapy. Cancer 1975, 35: 354-357. PMID: 1089470, DOI: 10.1002/1097-0142(197502)35:2<354::aid-cncr2820350209>3.0.co;2-2.Peer-Reviewed Original ResearchConceptsDiffuse histiocytic lymphomaComplete remissionLymphocytic lymphomaCombination chemotherapyHistiocytic lymphomaExtended disease-free survivalDisease-free survivalPatterns of relapseMonths of treatmentMaintenance chemotherapyRemission inductionLymph nodesLate recurrenceHistologic subgroupsHodgkin's lymphomaRemissionBone marrowLymphomaChemotherapyAggressive attemptsPatientsRelapseInitial siteTreatmentRecurrence
1974
Radiotherapeutic implications of prospective staging in non-Hodgkin's lymphoma.
Johnson R, Chretien P, O'Conor G, DeVita V, Thomas L. Radiotherapeutic implications of prospective staging in non-Hodgkin's lymphoma. Radiology 1974, 110: 655-7. PMID: 4811687, DOI: 10.1148/110.3.655.Peer-Reviewed Original Research