2024
Gray matters: ViT-GAN framework for identifying schizophrenia biomarkers linking structural MRI and functional network connectivity
Bi Y, Abrol A, Jia S, Sui J, Calhoun V. Gray matters: ViT-GAN framework for identifying schizophrenia biomarkers linking structural MRI and functional network connectivity. NeuroImage 2024, 297: 120674. PMID: 38851549, DOI: 10.1016/j.neuroimage.2024.120674.Peer-Reviewed Original ResearchFunctional network connectivityMedial prefrontal cortexBrain structuresFunctional network connectivity matricesPrefrontal cortexStructural MRINetwork connectivityGray matterSelf-attention mechanismGenerative adversarial networkDeep learning architectureBrain disordersDorsolateral prefrontal cortexResearch of schizophreniaNeural signal processingIdentified functional connectivityCross-domain analysisAttention mapsStructural biomarkersAdversarial networkLearning architectureDL-PFCICA algorithmSchizophrenia patientsHigh-dimensional fMRI dataCortical similarities in psychiatric and mood disorders identified in federated VBM analysis via COINSTAC
Rootes-Murdy K, Panta S, Kelly R, Romero J, Quidé Y, Cairns M, Loughland C, Carr V, Catts S, Jablensky A, Green M, Henskens F, Kiltschewskij D, Michie P, Mowry B, Pantelis C, Rasser P, Reay W, Schall U, Scott R, Watkeys O, Roberts G, Mitchell P, Fullerton J, Overs B, Kikuchi M, Hashimoto R, Matsumoto J, Fukunaga M, Sachdev P, Brodaty H, Wen W, Jiang J, Fani N, Ely T, Lorio A, Stevens J, Ressler K, Jovanovic T, van Rooij S, Federmann L, Jockwitz C, Teumer A, Forstner A, Caspers S, Cichon S, Plis S, Sarwate A, Calhoun V. Cortical similarities in psychiatric and mood disorders identified in federated VBM analysis via COINSTAC. Patterns 2024, 5: 100987. PMID: 39081570, PMCID: PMC11284501, DOI: 10.1016/j.patter.2024.100987.Peer-Reviewed Original ResearchPsychiatric disordersStructural neuroimaging studiesPattern of gray matterAutism spectrum disorderGray matterDepressive disorderMood disordersNeuroimaging studiesNeuroanatomical basisSubcortical regionsGM alterationsSpectrum disorderVBM analysisMental illnessGM patternsDisordersCollaborative InformaticsSchizophreniaMoodNeuroimaging Suite ToolkitAutismNeuroimagingVulnerabilityLarge-scale dataDeficits
2023
F71. NETWORK OF CO-METHYLATION ASSOCIATED WITH GREY MATTER MATURATION IN HUMAN ADOLESCENCE
Jensen D, Chen J, Turner J, Stephen J, Wang Y, Wilson T, Calhoun V, Liu J. F71. NETWORK OF CO-METHYLATION ASSOCIATED WITH GREY MATTER MATURATION IN HUMAN ADOLESCENCE. European Neuropsychopharmacology 2023, 75: s258-s259. DOI: 10.1016/j.euroneuro.2023.08.455.Peer-Reviewed Original ResearchStructural MRIBrain maturationNeuronal systemsCo-methylation network analysisPeriod of brain maturationAdolescent brain developmentAdolescent brain maturationPhases of neurodevelopmentIndependent component analysisGray matterHuman brain structureGM maturationDNAm changesCo-methylation modulesPrefrontal cortexExecutive functionFrontal poleGM volumeTime pointsSubjects aged 9Brain structuresCpG sitesSynaptic pruningBrain developmentDNA methylationEpigenetic associations with adolescent grey matter maturation and cognitive development
Jensen D, Chen J, Turner J, Stephen J, Wang Y, Wilson T, Calhoun V, Liu J. Epigenetic associations with adolescent grey matter maturation and cognitive development. Frontiers In Genetics 2023, 14: 1222619. PMID: 37529779, PMCID: PMC10390095, DOI: 10.3389/fgene.2023.1222619.Peer-Reviewed Original ResearchGM volume increaseGray matter maturationPatterns of brain maturationImprove cognitive performanceGray matterExecutive functionEpisodic memoryCognitive performanceCognitive testsBrain structuresProcessing speedBrain maturationCognitive AssessmentCognitive scoresBrain imagingAged 9BrainEpigenetic associationsAdolescentsLongitudinal cohortDNA methylationHuman neurodevelopmentDNA methylation of genesCytosine-phosphate-guanine (CpG) sitesBrain tissueFunctional and Structural Longitudinal Change Patterns in Adolescent Brain
Saha R, Saha D, Fu Z, Silva R, Calhoun V. Functional and Structural Longitudinal Change Patterns in Adolescent Brain. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2023, 00: 1-4. PMID: 38082649, DOI: 10.1109/embc40787.2023.10340079.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingStructural magnetic resonance imagingFunctional network connectivityWhole-brainGray matterBrain functional magnetic resonance imagingMagnetic resonance imagingAdolescent brainFunctional connectivityResonance imagingMultivariate patternsLongitudinal change patternsUnivariate changesAdolescentsLongitudinal changesBrainIncreasing ageFunctional changesComplementary techniquesNetwork connectivityNetwork Differential in Gaussian Graphical Models from Multimodal Neuroimaging Data*
Falakshahi H, Rokham H, Miller R, Liu J, Calhoun V. Network Differential in Gaussian Graphical Models from Multimodal Neuroimaging Data*. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2023, 00: 1-6. PMID: 38083176, DOI: 10.1109/embc40787.2023.10340856.Peer-Reviewed Original ResearchConceptsStatic functional network connectivityGaussian graphical modelsBrain disordersBrain graphsModel of schizophreniaMiddle temporal gyrusMechanisms of brain disordersFunctional network connectivityGray matter featuresBrain network analysisTemporal gyrusGroup graphPath-based analysisCerebellar regionsGraph theory approachSchizophreniaMultimodal studiesGraphical modelsNetwork connectivityNetwork differentiationGray matterGraphical metricsControl graphPairwise edgesBrain