2011
Validation of Genome-Wide Prostate Cancer Associations in Men of African Descent
Chang B, Spangler E, Gallagher S, Haiman C, Henderson B, Isaacs W, Benford M, Kidd L, Cooney K, Strom S, Ingles S, Stern M, Corral R, Joshi A, Xu J, Giri V, Rybicki B, Neslund-Dudas C, Kibel A, Thompson I, Leach R, Ostrander E, Stanford J, Witte J, Casey G, Eeles R, Hsing A, Chanock S, Hu J, John E, Park J, Stefflova K, Zeigler-Johnson C, Rebbeck T. Validation of Genome-Wide Prostate Cancer Associations in Men of African Descent. Cancer Epidemiology Biomarkers & Prevention 2011, 20: 23-32. PMID: 21071540, PMCID: PMC3110616, DOI: 10.1158/1055-9965.epi-10-0698.Peer-Reviewed Original ResearchConceptsGenome-wide association studiesProstate cancer susceptibility regionsGenome-wide significanceGWAS-identified lociCancer susceptibility lociGenetic etiologyProstate cancer susceptibility allelesEuropean descentGenetic variationCancer susceptibility allelesEuropean-descent populationsAssociation studiesSusceptibility lociGenotype dataLociSusceptibility regionsChromosome 8q24Susceptibility allelesDescent populationsRegion 2Prostate cancer associationRs12418451MSMBRs10993994Alleles
2003
Genome‐wide scan for prostate cancer susceptibility genes using families from the University of Michigan prostate cancer genetics project finds evidence for linkage on chromosome 17 near BRCA1
Lange E, Gillanders E, Davis C, Brown W, Campbell J, Jones M, Gildea D, Riedesel E, Albertus J, Freas‐Lutz D, Markey C, Giri V, Dimmer J, Montie J, Trent J, Cooney K. Genome‐wide scan for prostate cancer susceptibility genes using families from the University of Michigan prostate cancer genetics project finds evidence for linkage on chromosome 17 near BRCA1. The Prostate 2003, 57: 326-334. PMID: 14601029, DOI: 10.1002/pros.10307.Peer-Reviewed Original ResearchConceptsProstate cancer susceptibility genesCancer susceptibility genesSusceptibility genesCandidate genesGenome-wide scan dataGenome-wide analysisChromosome 17Michigan Prostate Cancer Genetics ProjectWhole-genome analysisCancer candidate genesProstate Cancer Genetics ProjectSubset of pedigreesStratified linkage analysesPrevious linkage studiesGenome analysisLinkage scanChromosome 1Genetic markersLinkage analysisAffected individualsGenesLinkage regionGenetics ProjectChromosome 17qProstate cancer families