Population genetics meets single-cell sequencing
Sumida TS, Hafler DA. Population genetics meets single-cell sequencing. Science 2022, 376: 134-135. PMID: 35389792, DOI: 10.1126/science.abq0426.Peer-Reviewed Original ResearchHyperosmotic stress response regulates interstitial homeostasis and pathogenic inflammation
Sumida T. Hyperosmotic stress response regulates interstitial homeostasis and pathogenic inflammation. The Journal Of Biochemistry 2023, 173: 159-166. PMID: 36722164, DOI: 10.1093/jb/mvad009.Peer-Reviewed Original ResearchConceptsHyperosmotic stress responseStress responseCell type-specific mannerFundamental cellular responsesType-specific mannerHeat shock proteinsCell cycle arrestImmune cell differentiationOsmolyte synthesisContext of diseaseHyperosmotic stressIon transportersHyperosmotic responseMetabolic remodelingMolecular mechanismsCellular responsesShock proteinsCell differentiationHuman diseasesCellular shrinkageCycle arrestAdaptative responseSpecific mannerTissue microenvironmentTissue immune homeostasis