2024
Barriers to Effective Infection Prevention in the Neonatal Intensive Care Unit
Weser V, Crocker A, Murray T, Wright J, Truesdell E, Ciaburri R, Marks A, Martinello R, Hieftje K, Team H. Barriers to Effective Infection Prevention in the Neonatal Intensive Care Unit. Advances In Neonatal Care 2024, 24: 475-484. PMID: 39196970, DOI: 10.1097/anc.0000000000001195.Peer-Reviewed Original ResearchConceptsPatients' family membersInfection preventionFamily membersGroup of nursesReduce nurses’ burdenHand hygieneHospital-wide surveyIntensive care unitInductive content analysisDesign of educational interventionsCare unitNeonatal intensive care unitImprove patient outcomesEffective infection preventionHH educationNursing burdenEducational interventionFrontline staffHospital staffNeonatal nursesIP educationPatient's familyRisk of infection transmissionFocus groupsIP behavior
2022
Prevalence of Chronic Diseases, Depression, and Stress Among US Childcare Professionals During the COVID-19 Pandemic
Elharake JA, Shafiq M, Cobanoglu A, Malik AA, Klotz M, Humphries JE, Murray T, Patel KM, Wilkinson D, Yildirim I, Diaz R, Rojas R, Cohen A, Lee A, Omer SB, Gilliam WS. Prevalence of Chronic Diseases, Depression, and Stress Among US Childcare Professionals During the COVID-19 Pandemic. Preventing Chronic Disease 2022, 19: e61. PMID: 36137183, PMCID: PMC9541678, DOI: 10.5888/pcd19.220132.Peer-Reviewed Original ResearchConceptsPhysical health conditionsMental healthHealth conditionsChronic diseasesDepression ratesCOVID-19 pandemicSex/gender disparityPublic health officialsChildcare professionalsSevere asthmaHeart diseaseUS adultsAsthma ratesSociodemographic characteristicsHealth officialsDepressionDiseaseNational representativenessLinear regression modelsPrevalenceHealthRegression modelsPandemicProfessionalsGender disparitiesImplementation of Pre-Admission Caregiver Testing for COVID-19.
He M, Peaper DR, Murray T, Ciaburri R, Doyle J, Loyal J. Implementation of Pre-Admission Caregiver Testing for COVID-19. Hospital Pediatrics 2022, 12: e326-e329. PMID: 36047308, DOI: 10.1542/hpeds.2022-006715.Peer-Reviewed Original ResearchConceptsCOVID-19 testingPatient cohortingSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmissionBed capacityCohorting of patientsInpatient pediatric admissionsCoronavirus disease 2019 (COVID-19) transmissionTertiary children's hospitalPediatric emergency departmentCOVID-19 positivityCOVID-19Procedural admissionsIsolation precautionsAsymptomatic adultsNegative childrenOverall incidencePediatric admissionsChildren's HospitalEmergency departmentHospitalized childrenDirect admissionInfection preventionOverall bed capacityInpatient unitPositive testAssociation of Child Masking With COVID-19–Related Closures in US Childcare Programs
Murray TS, Malik AA, Shafiq M, Lee A, Harris C, Klotz M, Humphries JE, Patel KM, Wilkinson D, Yildirim I, Elharake JA, Diaz R, Reyes C, Omer SB, Gilliam WS. Association of Child Masking With COVID-19–Related Closures in US Childcare Programs. JAMA Network Open 2022, 5: e2141227. PMID: 35084484, PMCID: PMC8796014, DOI: 10.1001/jamanetworkopen.2021.41227.Peer-Reviewed Original ResearchConceptsCOVID-19 casesLower riskImportant public health policy implicationsCOVID-19-related closuresPublic health policy implicationsChildren 2 yearsElectronic survey studyCenter-based childcare programsHealth policy implicationsSARS-CoV-2Survey studyChildcare professionalsMAIN OUTCOMEProgram closureHealth policyStudy periodRobust SEsBaselineChildcare programsCOVID-19Young childrenChildcare settingsChildrenPhysical distancingAssociation
2021
COVID-19 Vaccine Uptake Among US Child Care Providers
Patel KM, Malik AA, Lee A, Klotz M, Humphries JE, Murray T, Wilkinson D, Shafiq M, Yildirim I, Elharake JA, Diaz R, Reyes C, Omer SB, Gilliam WS. COVID-19 Vaccine Uptake Among US Child Care Providers. Pediatrics 2021, 148: e2021053813. PMID: 34452977, PMCID: PMC9277775, DOI: 10.1542/peds.2021-053813.Peer-Reviewed Original ResearchConceptsCOVID-19 vaccine uptakeVaccine uptakeCare providersChild care providersVaccination ratesSevere acute respiratory syndrome coronavirus 2Adult populationState public health leadersUS general adult populationAcute respiratory syndrome coronavirus 2General US adult populationRespiratory syndrome coronavirus 2Home-based child care programsSyndrome coronavirus 2US adult populationGeneral adult populationCross-sectional surveyPublic health implicationsPublic health leadersAnnual household incomeCoronavirus 2Care settingsInclusion criteriaCare programChild care settingsCOVID-19 Transmission in US Child Care Programs
Gilliam WS, Malik AA, Shafiq M, Klotz M, Reyes C, Humphries JE, Murray T, Elharake JA, Wilkinson D, Omer SB. COVID-19 Transmission in US Child Care Programs. Pediatrics 2021, 147: e2020031971. PMID: 33055228, DOI: 10.1542/peds.2020-031971.Peer-Reviewed Original ResearchConceptsCare programCOVID-19 transmissionCare providersCOVID-19Child care programsChild care providersPropensity score-matched case-control analysisCOVID-19 outcomesLogistic regression analysisCase-control analysisUS COVID-19 pandemicChild carePotential confoundersElevated riskHome-based providersCareUS pandemicRegression analysisCOVID-19 pandemicDegree of exposureExposureMonthsOutcomesEarly monthsProviders
2020
Unmasking symptomatic dermatographism in the time of COVID-19
Wong KH, Murray T, Osborn R, Soffer GK. Unmasking symptomatic dermatographism in the time of COVID-19. Postgraduate Medical Journal 2020, 97: 402-402. PMID: 32913035, PMCID: PMC10016992, DOI: 10.1136/postgradmedj-2020-138688.Peer-Reviewed Case Reports and Technical Notes
2014
ESBL-producing Escherichia coli and Klebsiella pneumoniae at a tertiary care hospital in Saudi Arabia.
Somily AM, Habib HA, Absar MM, Arshad MZ, Manneh K, Al Subaie SS, Al Hedaithy MA, Sayyed SB, Shakoor Z, Murray TS. ESBL-producing Escherichia coli and Klebsiella pneumoniae at a tertiary care hospital in Saudi Arabia. The Journal Of Infection In Developing Countries 2014, 8: 1129-36. PMID: 25212077, DOI: 10.3855/jidc.4292.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAnti-Bacterial AgentsBeta-LactamasesBeta-LactamsChildChild, PreschoolEscherichia coliEscherichia coli InfectionsFemaleHumansInfantKlebsiella InfectionsKlebsiella pneumoniaeMaleMicrobial Sensitivity TestsMiddle AgedProspective StudiesSaudi ArabiaTertiary Care CentersYoung AdultConceptsTertiary care hospitalK. pneumoniaeCare hospitalStudy periodClavulanic acidKing Khalid University HospitalDeep wound swabsFrequency of ESBLK. pneumoniae isolatesESBL-producing E. coliExtended-spectrum β-lactamasesSterile body fluidsAnti-microbial susceptibilityESBL-producing isolatesOverall frequency rateE. coli resistanceESBL E. coliWound swabsUniversity HospitalEtest stripsPneumoniae isolatesBlood samplesSuperficial swabsAntibiotic susceptibilityFrequency rate
2013
Reduced Caveolin-1 Promotes Hyperinflammation due to Abnormal Heme Oxygenase-1 Localization in Lipopolysaccharide-Challenged Macrophages with Dysfunctional Cystic Fibrosis Transmembrane Conductance Regulator
Zhang PX, Murray TS, Villella VR, Ferrari E, Esposito S, D'Souza A, Raia V, Maiuri L, Krause DS, Egan ME, Bruscia EM. Reduced Caveolin-1 Promotes Hyperinflammation due to Abnormal Heme Oxygenase-1 Localization in Lipopolysaccharide-Challenged Macrophages with Dysfunctional Cystic Fibrosis Transmembrane Conductance Regulator. The Journal Of Immunology 2013, 190: 5196-5206. PMID: 23606537, PMCID: PMC3711148, DOI: 10.4049/jimmunol.1201607.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAnimalsCaveolin 1Cells, CulturedChildChild, PreschoolCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorFemaleHeme Oxygenase-1HumansInflammationLipopolysaccharidesLung DiseasesMacrophagesMaleMembrane ProteinsMiceMice, KnockoutNasal PolypsReactive Oxygen SpeciesSignal TransductionToll-Like Receptor 4Young AdultConceptsCav-1 expressionHeme oxygenase-1Dysfunctional cystic fibrosis transmembrane conductance regulatorCystic fibrosis transmembrane conductance regulatorCell surfaceFibrosis transmembrane conductance regulatorProtein caveolin-1Cellular redox statusCell surface localizationCellular oxidative stateTransmembrane conductance regulatorHO-1 enzymePositive feed-forward loopCystic fibrosis macrophagesNegative regulatorCaveolin-1Conductance regulatorCell survivalHO-1 deliverySurface localizationRedox statusMΦ responsesHO-1/CO pathwayPathwayPotential target
2012
The Ability of Virulence Factor Expression by Pseudomonas aeruginosa to Predict Clinical Disease in Hospitalized Patients
Ledizet M, Murray TS, Puttagunta S, Slade MD, Quagliarello VJ, Kazmierczak BI. The Ability of Virulence Factor Expression by Pseudomonas aeruginosa to Predict Clinical Disease in Hospitalized Patients. PLOS ONE 2012, 7: e49578. PMID: 23152923, PMCID: PMC3495863, DOI: 10.1371/journal.pone.0049578.Peer-Reviewed Original ResearchConceptsP. aeruginosa infectionAeruginosa infectionBacterial factorsHospitalized patientsUrinary tractPositive P. aeruginosa culturesP. aeruginosaUrinary tract cathetersP. aeruginosa isolatesLogistic regression modelsPseudomonas aeruginosaProspective cohortDiabetes mellitusSubgroup analysisClinical dataTreatment decisionsClinical diseaseAeruginosa isolatesAnimal modelsPatientsClinical sitesFactor expressionInfectionHost factorsP. aeruginosa cultures
2011
Relapse of polymicrobial endocarditis in an intravenous drug user.
Wang’ondu R, Murray TS. Relapse of polymicrobial endocarditis in an intravenous drug user. The Yale Journal Of Biology And Medicine 2011, 84: 321-4. PMID: 21966051, PMCID: PMC3178863.Peer-Reviewed Original ResearchConceptsIntravenous drug usersInfective endocarditisDrug usersMale intravenous drug usersPolymicrobial infective endocarditisAppropriate antimicrobial therapyPolymicrobial endocarditisClinical entityAntimicrobial therapyStreptococcus constellatusEikenella corrodensE. corrodensEndocarditisS. constellatusCausative agentCorrodensConstellatus
2010
Swarming motility, secretion of type 3 effectors and biofilm formation phenotypes exhibited within a large cohort of Pseudomonas aeruginosa clinical isolates
Murray TS, Ledizet M, Kazmierczak BI. Swarming motility, secretion of type 3 effectors and biofilm formation phenotypes exhibited within a large cohort of Pseudomonas aeruginosa clinical isolates. Journal Of Medical Microbiology 2010, 59: 511-520. PMID: 20093376, PMCID: PMC2855384, DOI: 10.1099/jmm.0.017715-0.Peer-Reviewed Original Research