2009
Pseudomonas aeruginosa OspR is an oxidative stress sensing regulator that affects pigment production, antibiotic resistance and dissemination during infection
Lan L, Murray TS, Kazmierczak BI, He C. Pseudomonas aeruginosa OspR is an oxidative stress sensing regulator that affects pigment production, antibiotic resistance and dissemination during infection. Molecular Microbiology 2009, 75: 76-91. PMID: 19943895, PMCID: PMC2881571, DOI: 10.1111/j.1365-2958.2009.06955.x.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SubstitutionAnimalsAnti-Bacterial AgentsBeta-Lactam ResistanceBeta-LactamsFemaleGene DeletionGene Expression Regulation, BacterialGlutathione PeroxidaseHydrogen PeroxideMiceMice, Inbred C57BLModels, BiologicalMutagenesis, Site-DirectedOxidative StressPigments, BiologicalPneumoniaPseudomonas aeruginosaPseudomonas InfectionsQuorum SensingRepressor ProteinsSignal TransductionStress, PhysiologicalTyrosineVirulenceConceptsOxidative stress sensingCys-24Stress sensingPigment productionNull mutant strainOxidative stressSerine substitution mutantsGlobal regulatorPromoter DNASubstitution mutantsAdditional genesInside hostsQuorum sensingCys residuesMutant strainConstitutive expressionMultiple pathwaysRegulatory effectsBeta-lactam resistanceGenesSignificant inductionRegulatorTyrosine metabolismOSPRP. aeruginosa
1998
Characterization of dacC, Which Encodes a New Low-Molecular-Weight Penicillin-Binding Protein in Bacillus subtilis
Pedersen L, Murray T, Popham D, Setlow P. Characterization of dacC, Which Encodes a New Low-Molecular-Weight Penicillin-Binding Protein in Bacillus subtilis. Journal Of Bacteriology 1998, 180: 4967-4973. PMID: 9733705, PMCID: PMC107527, DOI: 10.1128/jb.180.18.4967-4973.1998.Peer-Reviewed Original ResearchConceptsWeight penicillin-binding proteinsPenicillin-binding proteinsBacillus subtilis genome sequencing projectB. subtilis chromosomeGenome sequencing projectsWild-type cellsWild-type sporesInsertional mutantsPenicillin binding proteinsSequencing projectsSequence homologyUnknown functionBacillus subtilisEscherichia coliGenesPBP genesProteinSame heat resistanceOutgrowth kineticsExpressionSigmaHMutantsChromosomesHomologyPromoter
1996
Identification and characterization of pbpC, the gene encoding Bacillus subtilis penicillin-binding protein 3
Murray T, Popham D, Setlow P. Identification and characterization of pbpC, the gene encoding Bacillus subtilis penicillin-binding protein 3. Journal Of Bacteriology 1996, 178: 6001-6005. PMID: 8830698, PMCID: PMC178458, DOI: 10.1128/jb.178.20.6001-6005.1996.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceBacillus subtilisBacterial ProteinsBase SequenceCarrier ProteinsCell DivisionGene ExpressionGenes, BacterialHexosyltransferasesMolecular Sequence DataMultienzyme ComplexesMuramoylpentapeptide CarboxypeptidaseMutagenesisPenicillin-Binding ProteinsPeptidyl TransferasesRecombinant Fusion ProteinsRestriction MappingSpecies SpecificitySpores, BacterialTranscription, GeneticConceptsSignificant sequence similarityVegetative cell wallTranscriptional fusionsRedundant functionsDouble mutantLog-phase growthSequence similaritySequencing projectsPenicillin-binding protein 3Peptidoglycan structureSpore cortexCell wallB. subtilisBacillus subtilisGenesMajor promoterSpore germinationWeight PBPsSporulationCell morphologyFurther upstreamProtein 3GerminationSpore heat resistanceSubtilis