1988
Neurotoxin-Binding Site on The Acetylcholine Receptor
Lentz T, Wilson P. Neurotoxin-Binding Site on The Acetylcholine Receptor. International Review Of Neurobiology 1988, 29: 117-160. PMID: 3042662, DOI: 10.1016/s0074-7742(08)60085-9.Peer-Reviewed Original ResearchConceptsAcetylcholine-binding siteBinding of acetylcholineToxin-binding sitesPrimary amino acid sequenceAmino acid sequenceAcetylcholine receptorsCation-selective channelsAcid sequenceGenetic engineeringEssential functionsChemical signalsConformational changesNicotinic acetylcholine receptorsUse of toxinsMotor nerve terminalsMuscle cellsAChRCuraremimetic neurotoxinsBindingNeurotransmitter acetylcholineNeuromuscular junctionNicotinic AChRsReceptorsNerve terminalsHigh affinityChapter 9 Synthetic Peptides in the Study of the Nicotinic Acetylcholine Receptor
Hawrot E, Colson K, Lentz T, Wilson P. Chapter 9 Synthetic Peptides in the Study of the Nicotinic Acetylcholine Receptor. Current Topics In Membranes 1988, 33: 165-195. DOI: 10.1016/s0070-2161(08)60899-0.Peer-Reviewed Original Research
1986
Mapping of the Alpha‐Bungarotoxin Binding Site on the Primary Amino Acid Sequence of the Torpedo Acetylcholine Receptor
WILSON P, LENTZ T, HAWROT E. Mapping of the Alpha‐Bungarotoxin Binding Site on the Primary Amino Acid Sequence of the Torpedo Acetylcholine Receptor. Annals Of The New York Academy Of Sciences 1986, 463: 243-246. DOI: 10.1111/j.1749-6632.1986.tb21559.x.Peer-Reviewed Original Research
1985
Determination of the primary amino acid sequence specifying the alpha-bungarotoxin binding site on the alpha subunit of the acetylcholine receptor from Torpedo californica.
Wilson P, Lentz T, Hawrot E. Determination of the primary amino acid sequence specifying the alpha-bungarotoxin binding site on the alpha subunit of the acetylcholine receptor from Torpedo californica. Proceedings Of The National Academy Of Sciences Of The United States Of America 1985, 82: 8790-8794. PMID: 3866252, PMCID: PMC391523, DOI: 10.1073/pnas.82.24.8790.Peer-Reviewed Original ResearchConceptsBungarotoxin-binding sitesPrimary amino acid sequenceAmino acid sequenceAlpha subunitAmino acidsAcid sequenceAcetylcholine receptorsNicotinic acetylcholine receptorsAlpha-bungarotoxin binding sitesEndoglycosidase H.Residues 173Torpedo californicaV8 proteaseSubunitsOligosaccharide chainsProteolytic fragmentsBinding sitesPresumed siteSize of fragmentsFragmentsSynthetic peptidesSequenceBind 125IDigestionMajor determinant