Effect of endoscopic ultrasound guided celiac plexus block on the palliation of pain in chronic pancreatitis (EPOCH Trial): study protocol for a randomized multicenter sham-controlled trial {1}
Wilcox C, Bang J, Buxbaum J, Gardner T, Hawes R, Kedia P, Mardini S, Muniraj T, Navaneethan U, Oza V, Tarnasky P, Thakkar S, Waxman I, Varadarajulu S. Effect of endoscopic ultrasound guided celiac plexus block on the palliation of pain in chronic pancreatitis (EPOCH Trial): study protocol for a randomized multicenter sham-controlled trial {1}. Trials 2024, 25: 676. PMID: 39396987, PMCID: PMC11472533, DOI: 10.1186/s13063-024-08478-y.Peer-Reviewed Original ResearchMeSH KeywordsAbdominal PainAutonomic Nerve BlockCeliac PlexusEndosonographyHumansMulticenter Studies as TopicNerve BlockPain MeasurementPalliative CarePancreatitis, ChronicProspective StudiesRandomized Controlled Trials as TopicTime FactorsTreatment OutcomeUltrasonography, InterventionalUnited StatesConceptsCeliac plexus blockAbdominal painChronic pancreatitisVisual analog scalePlexus blockSham-controlled trialRandomized sham-controlled trialEndoscopic ultrasound-guided celiac plexus blockEffectiveness of endoscopic ultrasoundBrief Pain Inventory Short FormDocumented chronic pancreatitisPainful chronic pancreatitisPalliation of painTime of EUSTreatment of abdominal painPain scoresBPI-SFSteroid combinationsAnalog scaleEndoscopic ultrasoundProspective studyCeliac plexusRandomized trialsShort formPancreatitis