2023
Estimated rates of progression to tuberculosis disease for persons infected with Mycobacterium tuberculosis in the United States
Ekramnia M, Li Y, Haddad M, Marks S, Kammerer J, Swartwood N, Cohen T, Miller J, Horsburgh C, Salomon J, Menzies N. Estimated rates of progression to tuberculosis disease for persons infected with Mycobacterium tuberculosis in the United States. Epidemiology 2023, 35: 164-173. PMID: 38290139, PMCID: PMC10832387, DOI: 10.1097/ede.0000000000001707.Peer-Reviewed Original ResearchConceptsInterferon-gamma release assayNational Health and Nutrition Examination SurveyHealth and Nutrition Examination SurveyUS-born statusNational TB Surveillance SystemReactivation TBNutrition Examination SurveyInterferon-gammaIGRA sensitivityTB surveillance systemProgression to tuberculosis diseaseNationally representative dataEnd-stage renal diseaseReactivation rateAmerican Community SurveyExamination SurveyPerson yearsRace-ethnicityUS populationTB ratesTB incidenceCommunity SurveyRepresentative dataSurveillance systemRelease assay
2022
Neighbourhood prevalence-to-notification ratios for adult bacteriologically-confirmed tuberculosis reveals hotspots of underdiagnosis in Blantyre, Malawi
Khundi M, Carpenter JR, Corbett EL, Feasey HRA, Soko RN, Nliwasa M, Twabi H, Chiume L, Burke RM, Horton KC, Dodd PJ, Cohen T, MacPherson P. Neighbourhood prevalence-to-notification ratios for adult bacteriologically-confirmed tuberculosis reveals hotspots of underdiagnosis in Blantyre, Malawi. PLOS ONE 2022, 17: e0268749. PMID: 35605004, PMCID: PMC9126376, DOI: 10.1371/journal.pone.0268749.Peer-Reviewed Original ResearchConceptsCase notification ratesPrevalence surveyNotification ratioNeighbourhood prevalenceTB case notification ratesXpert MTB/RIFCase-finding interventionsTrue disease burdenChest X-ray screeningTB prevalence surveyTB surveillance systemMTB/RIFDiagnosis of tuberculosisSputum smear microscopyTB clinicTB patientsRespiratory infectionsTB prevalenceDisease burdenNotification ratesSmear microscopyX-ray screeningTuberculosisPrevalenceUrban tuberculosis
2021
Trends, Mechanisms, and Racial/Ethnic Differences of Tuberculosis Incidence in the US-Born Population Aged 50 Years or Older in the United States
Kim S, Cohen T, Horsburgh CR, Miller JW, Hill AN, Marks SM, Li R, Kammerer JS, Salomon JA, Menzies NA. Trends, Mechanisms, and Racial/Ethnic Differences of Tuberculosis Incidence in the US-Born Population Aged 50 Years or Older in the United States. Clinical Infectious Diseases 2021, 74: 1594-1603. PMID: 34323959, PMCID: PMC8799750, DOI: 10.1093/cid/ciab668.Peer-Reviewed Original ResearchConceptsAnnual percentage declineIncidence rateRemote infectionBirth cohortOlder individualsPercentage declineUS National TB Surveillance SystemAverage annual percentage declineNational TB Surveillance SystemRace/ethnicity strataTB incidence rateTB surveillance systemLow-incidence settingsEthnic differencesEarlier birth cohortsRecent birth cohortsRace/ethnicityOverall cohortTB casesTB incidenceIncidence settingsRecent infectionTB ratesTuberculosis incidenceRisk factors