2024
Stiffening of the human proximal pulmonary artery with increasing age
Manning E, Mishall P, Ramachandra A, Hassab A, Lamy J, Peters D, Murphy T, Heerdt P, Singh I, Downie S, Choudhary G, Tellides G, Humphrey J. Stiffening of the human proximal pulmonary artery with increasing age. Physiological Reports 2024, 12: e16090. PMID: 38884325, PMCID: PMC11181131, DOI: 10.14814/phy2.16090.Peer-Reviewed Original ResearchConceptsProximal pulmonary arteriesPulmonary arteryAge-related stiffeningRight ventricular ejection fractionVentricular ejection fractionMean wall thicknessEjection fractionNo significant differenceSystemic circulationLuminal caliberDiffusing capacityArterial stiffeningIncreasing ageSignificant differenceDistensionArteryWall thicknessAdverse effectsWall strainVessel diameterCyclic biaxial strainOrgan donorsAgeMicrostructural remodeling
2023
Acute hospital use in older adults following the 2015 Dutch reform of long-term care: an interrupted time series analysis
Wammes J, Bakx P, Wouterse B, Buurman B, Murphy T, Vroomen J. Acute hospital use in older adults following the 2015 Dutch reform of long-term care: an interrupted time series analysis. The Lancet Healthy Longevity 2023, 4: e257-e264. PMID: 37269863, PMCID: PMC10316520, DOI: 10.1016/s2666-7568(23)00064-8.Peer-Reviewed Original ResearchConceptsIncident rate ratiosInterrupted time series analysisHospital dataOlder adultsAcute hospitalisationAcute hospital useAverage hospital lengthNational hospital dataMonthly rateLong-term careSupplementary Materials sectionAdvancing Translational SciencesHospital lengthHospital admissionAverage LOSLTC reformHospitalisationCurative careHospital useLongitudinal increaseRate ratioMedical specialistsNational InstituteAdultsLOS