2008
Type 3 Deiodinase in Hypoxia: To Cool or to Kill?
Diano S, Horvath TL. Type 3 Deiodinase in Hypoxia: To Cool or to Kill? Cell Metabolism 2008, 7: 363-364. PMID: 18460327, DOI: 10.1016/j.cmet.2008.04.008.Peer-Reviewed Original Research
2007
A Central Thermogenic-like Mechanism in Feeding Regulation: An Interplay between Arcuate Nucleus T3 and UCP2
Coppola A, Liu ZW, Andrews ZB, Paradis E, Roy MC, Friedman JM, Ricquier D, Richard D, Horvath TL, Gao XB, Diano S. A Central Thermogenic-like Mechanism in Feeding Regulation: An Interplay between Arcuate Nucleus T3 and UCP2. Cell Metabolism 2007, 5: 21-33. PMID: 17189204, PMCID: PMC1783766, DOI: 10.1016/j.cmet.2006.12.002.Peer-Reviewed Original ResearchMeSH KeywordsAgouti-Related ProteinAnimalsArcuate Nucleus of HypothalamusEatingFastingFeeding BehaviorGreen Fluorescent ProteinsGuanosine DiphosphateHypothalamusIntercellular Signaling Peptides and ProteinsIodide PeroxidaseIon ChannelsMiceMice, Inbred C57BLMice, KnockoutMitochondriaMitochondrial ProteinsNeurogliaNeuronsNeuropeptide YProto-Oncogene Proteins c-fosThermogenesisTriiodothyronineUncoupling Protein 2ConceptsUncoupling protein 2Mitochondrial uncoupling protein 2Thyroid hormone productionProtein activityType 2 deiodinaseMitochondrial proliferationNeuropeptide YArcuate nucleusPhysiological roleMitochondrial uncouplingUCP2 activationProtein 2Hormone productionNPY/AgRP neuronsPhysiological significanceActive thyroid hormoneHypothalamic arcuate nucleusHypothalamic neuronal networksGlial cellsRebound feedingAgRP neuronsOrexigenic neuronsDeiodinaseDII activityPeripheral tissues
1998
Monosynaptic Pathway Between the Arcuate Nucleus Expressing Glial Type II Iodothyronine 5′‐Deiodinase mRNA and the Median Eminence‐Projective TRH Cells of the Rat Paraventricular Nucleus
Diano S, Naftolin F, Goglia F, Csernus V, Horvath T. Monosynaptic Pathway Between the Arcuate Nucleus Expressing Glial Type II Iodothyronine 5′‐Deiodinase mRNA and the Median Eminence‐Projective TRH Cells of the Rat Paraventricular Nucleus. Journal Of Neuroendocrinology 1998, 10: 731-742. PMID: 9792325, DOI: 10.1046/j.1365-2826.1998.00204.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsArcuate Nucleus of HypothalamusFemaleFluorescent DyesImmunohistochemistryIn Situ HybridizationIodide PeroxidaseIsoenzymesMaleMedian EminenceNeural PathwaysNeurogliaParaventricular Hypothalamic NucleusPhytohemagglutininsRatsRats, Sprague-DawleyRNA, MessengerStilbamidinesThyrotropin-Releasing HormoneFasting-Induced Increase in Type II Iodothyronine Deiodinase Activity and Messenger Ribonucleic Acid Levels Is Not Reversed by Thyroxine in the Rat Hypothalamus
Diano S, Naftolin F, Goglia F, Horvath T. Fasting-Induced Increase in Type II Iodothyronine Deiodinase Activity and Messenger Ribonucleic Acid Levels Is Not Reversed by Thyroxine in the Rat Hypothalamus. Endocrinology 1998, 139: 2879-2884. PMID: 9607797, DOI: 10.1210/endo.139.6.6062.Peer-Reviewed Original Research