Splenic Irradiation as a Component of a Reduced-Intensity Conditioning Regimen for Hematopoietic Stem Cell Transplantation in Myelofibrosis with Massive Splenomegaly
Ito T, Akagi K, Kondo T, Kawabata H, Ichinohe T, Takaori-Kondo A. Splenic Irradiation as a Component of a Reduced-Intensity Conditioning Regimen for Hematopoietic Stem Cell Transplantation in Myelofibrosis with Massive Splenomegaly. The Tohoku Journal Of Experimental Medicine 2012, 228: 295. PMID: 23117264, DOI: 10.1620/tjem.228.295.Peer-Reviewed Original ResearchMeSH KeywordsDisease ProgressionFatal OutcomeFemaleHematopoietic Stem Cell TransplantationHumansMaleMiddle AgedPrimary MyelofibrosisSpleenSplenomegalyTransplantation ConditioningConceptsHematopoietic stem cell transplantationAllogeneic hematopoietic stem cell transplantationStem cell transplantationSplenic irradiationMassive splenomegalyCell transplantationSurgical morbidityPrimary myelofibrosisPeripheral blood stem cell transplantationBlood stem cell transplantationReduced-intensity conditioning regimenReduced-intensity conditioning regimensUnrelated bone marrow transplantationPost-essential thrombocythemia myelofibrosisOnly curative strategyHLA-identical siblingsProportion of patientsTime of transplantationBone marrow transplantationBone marrow fibrosisDonor cell engraftmentSimilar clinical conditionsConditioning regimenConditioning regimensElderly patients