Splenic Irradiation as a Component of a Reduced-Intensity Conditioning Regimen for Hematopoietic Stem Cell Transplantation in Myelofibrosis with Massive Splenomegaly
Ito T, Akagi K, Kondo T, Kawabata H, Ichinohe T, Takaori-Kondo A. Splenic Irradiation as a Component of a Reduced-Intensity Conditioning Regimen for Hematopoietic Stem Cell Transplantation in Myelofibrosis with Massive Splenomegaly. The Tohoku Journal Of Experimental Medicine 2012, 228: 295. PMID: 23117264, DOI: 10.1620/tjem.228.295.Peer-Reviewed Original ResearchConceptsHematopoietic stem cell transplantationAllogeneic hematopoietic stem cell transplantationStem cell transplantationSplenic irradiationMassive splenomegalyCell transplantationSurgical morbidityPrimary myelofibrosisPeripheral blood stem cell transplantationBlood stem cell transplantationReduced-intensity conditioning regimenReduced-intensity conditioning regimensUnrelated bone marrow transplantationPost-essential thrombocythemia myelofibrosisOnly curative strategyHLA-identical siblingsProportion of patientsTime of transplantationBone marrow transplantationBone marrow fibrosisDonor cell engraftmentSimilar clinical conditionsConditioning regimenConditioning regimensElderly patients