2019
1346-P: Longitudinal Evaluation of Cognitive Functioning in Young Children with Type 1 Diabetes: Persistent Effects on IQ and Vocabulary
WEINZIMER S, AMBROSINO J, CATO A, JO B, ENGLERT K, WHITE N, ARBELAEZ A, HERSHEY T, FOX L, TSALIKIAN E, TANSEY M, BUCKINGHAM B, AYE T, WILSON D, TAMBORLANE W, REISS A, MAURAS N. 1346-P: Longitudinal Evaluation of Cognitive Functioning in Young Children with Type 1 Diabetes: Persistent Effects on IQ and Vocabulary. Diabetes 2019, 68 DOI: 10.2337/db19-1346-p.Peer-Reviewed Original ResearchSpouse/partnerFull Scale IQVerbal IQSignificant cognitive differencesYoung childrenResearch supportCognitive differencesCognitive functioningCognitive dataProcessing speedParental IQNeuropsychological testingIQBrain maturationLower scoresSelfVocabularyHuman developmentChildrenCritical periodLongitudinal evaluationMixed effectsCognitionPartnersVIQ
2015
Variations in Brain Volume and Growth in Young Children With Type 1 Diabetes
Mazaika PK, Weinzimer SA, Mauras N, Buckingham B, White NH, Tsalikian E, Hershey T, Cato A, Aye T, Fox L, Wilson DM, Tansey MJ, Tamborlane W, Peng D, Raman M, Marzelli M, Reiss AL. Variations in Brain Volume and Growth in Young Children With Type 1 Diabetes. Diabetes 2015, 65: 476-485. PMID: 26512024, PMCID: PMC4747456, DOI: 10.2337/db15-1242.Peer-Reviewed Original ResearchConceptsEarly-onset type 1 diabetesType 1 diabetesBlood glucose levelsWhite matter volumeGlucose levelsMatter volumeTime pointsBrain volumeAge-matched control subjectsCortical gray matter volumeMeasures of hyperglycemiaMean HbA1c levelCurrent treatment guidelinesManagement of diabetesRapid brain maturationGray matter volumeTime of scanCortical surface areaHbA1c levelsTreatment guidelinesControl subjectsGlycemic variationsLongitudinal time pointsBrain maturationDiabetes