Featured Publications
Oxytocin under opioid antagonism leads to supralinear enhancement of social attention
Dal Monte O, Piva M, Anderson KM, Tringides M, Holmes AJ, Chang SWC. Oxytocin under opioid antagonism leads to supralinear enhancement of social attention. Proceedings Of The National Academy Of Sciences Of The United States Of America 2017, 114: 5247-5252. PMID: 28461466, PMCID: PMC5441805, DOI: 10.1073/pnas.1702725114.Peer-Reviewed Original ResearchConceptsSocial attentionMutual eye contactSocial cognitionReward receiptParticular social importanceEfficacy of oxytocinEye contactSocial dysfunctionOpioid antagonismSocial contextGaze interactionHuman brainEntire sessionOxytocinΚ-opioid receptor geneFacial regionOT geneAttentionCognitionSocial importanceStrong effectMonkeysOpioid systemSessionsContext
2022
Interplay between the oxytocin and opioid systems in regulating social behaviour
Putnam PT, Chang SWC. Interplay between the oxytocin and opioid systems in regulating social behaviour. Philosophical Transactions Of The Royal Society B Biological Sciences 2022, 377: 20210050. PMID: 35858101, PMCID: PMC9272147, DOI: 10.1098/rstb.2021.0050.Peer-Reviewed Original ResearchOxytocin does not stand alone
Putnam PT, Chang SWC. Oxytocin does not stand alone. Philosophical Transactions Of The Royal Society B Biological Sciences 2022, 377: 20210047. PMID: 35858106, PMCID: PMC9272150, DOI: 10.1098/rstb.2021.0047.Peer-Reviewed Original ResearchOxytocinSocial neuroscience: Staying bonded over oxytocin and endocannabinoids
Nair AR, Chang SWC. Social neuroscience: Staying bonded over oxytocin and endocannabinoids. Current Biology 2022, 32: r228-r231. PMID: 35290773, DOI: 10.1016/j.cub.2022.02.009.Peer-Reviewed Original Research
2019
Combinatorial Oxytocin Neuropharmacology in Social Cognition
Fan S, Weinberg-Wolf H, Piva M, Dal Monte O, Chang SWC. Combinatorial Oxytocin Neuropharmacology in Social Cognition. Trends In Cognitive Sciences 2019, 24: 8-12. PMID: 31735541, DOI: 10.1016/j.tics.2019.10.004.Peer-Reviewed Original Research
2018
An integrated framework for the role of oxytocin in multistage social decision‐making
Piva M, Chang SWC. An integrated framework for the role of oxytocin in multistage social decision‐making. American Journal Of Primatology 2018, 80: e22735. PMID: 29350419, PMCID: PMC6053333, DOI: 10.1002/ajp.22735.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBehavior, AnimalCognitionDecision MakingHumansOxytocinPrimatesRodentiaSocial BehaviorConceptsEffects of oxytocinSocial behaviorWithdrawal hypothesisSocial salience hypothesisCertain social situationsRole of oxytocinInfluence of oxytocinNeural evidenceProsocial actionsSocial stimuliProsocial choicesApproach behaviorSalience hypothesisSocial salienceSocial decisionsAntisocial behaviorSocial situationsOxytocin administrationWithdrawal behaviorSensory inputBehavioral outputSensory perceptionOverarching theoryDisparate theoriesProminent hypothesis
2012
Inhaled oxytocin amplifies both vicarious reinforcement and self reinforcement in rhesus macaques (Macaca mulatta)
Chang SW, Barter JW, Ebitz RB, Watson KK, Platt ML. Inhaled oxytocin amplifies both vicarious reinforcement and self reinforcement in rhesus macaques (Macaca mulatta). Proceedings Of The National Academy Of Sciences Of The United States Of America 2012, 109: 959-964. PMID: 22215593, PMCID: PMC3271866, DOI: 10.1073/pnas.1114621109.Peer-Reviewed Original ResearchConceptsDelivery of rewardTypical social behaviorsProsocial choicesDecision latenciesObservational learningSpecies-typical social behaviorsNeural mechanismsSelfish choicesVicarious reinforcementSocial behaviorDistinct contextsDonation behaviorHuman behaviorNeural modelRewardSocial awarenessSelf-ReinforcementOxytocinPrairie volesSelfMonogamous onesRhesus macaquesOwn experienceEmpathyAttention