2021
Increasing Central Serotonin with 5-hydroxytryptophan Disrupts the Inhibition of Social Gaze in Nonhuman Primates
Weinberg-Wolf HB, Fagan N, Dal Monte O, Chang SWC. Increasing Central Serotonin with 5-hydroxytryptophan Disrupts the Inhibition of Social Gaze in Nonhuman Primates. Journal Of Neuroscience 2021, 42: 670-681. PMID: 34862190, PMCID: PMC8805615, DOI: 10.1523/jneurosci.0413-21.2021.Peer-Reviewed Original ResearchConceptsSocial gaze behaviorAbility of monkeysSocial gazeGaze behaviorMotivational stateControl imagesReaction timeCentral serotonin levelsNonhuman primatesSocial orientingGaze responsesSerotonergic interventionsModulatory relationshipCausal evidenceEye movementsTranslational insightsGazeDistinct aspectsDisruptive effectsBehavioral changesSerotonergic systemPupil constrictionCausal impactCentral serotoninFlexible orientation
2019
Differences in how macaques monitor others: Does serotonin play a central role?
Weinberg‐Wolf H, Chang SWC. Differences in how macaques monitor others: Does serotonin play a central role? Wiley Interdisciplinary Reviews Cognitive Science 2019, 10: e1494. PMID: 30775852, PMCID: PMC6570566, DOI: 10.1002/wcs.1494.Peer-Reviewed Original ResearchMeSH KeywordsAggressionAnimalsBiological EvolutionHumansMacacaSerotoninSocial BehaviorSpecies SpecificityConceptsDecision-making psychologyCognitive BiologySocial attentionSocial competenciesSocial informationSocial monitoringEvolutionary rootsPsychologySocial toleranceNeuroscienceAggressionDominance behaviorRole of serotoninField of primatologySerotonergic functionCognitionConspecificsPrimatesPrimatologyMacaquesCompetenciesDifferencesAttentionCentral roleResource opportunities
2018
The effects of 5-hydroxytryptophan on attention and central serotonin neurochemistry in the rhesus macaque
Weinberg-Wolf H, Fagan NA, Anderson GM, Tringides M, Dal Monte O, Chang SWC. The effects of 5-hydroxytryptophan on attention and central serotonin neurochemistry in the rhesus macaque. Neuropsychopharmacology 2018, 43: 1589-1598. PMID: 29463909, PMCID: PMC5983545, DOI: 10.1038/s41386-017-0003-7.Peer-Reviewed Original ResearchConceptsSerotonergic interventionsSalient facial featuresCentral serotonergic functioningCisternal cerebrospinal fluidBaseline attentionCognitive operationsSerotonin's roleIndividual differencesBi-directional effectsAutonomic arousalSaline sessionsImmediate serotonin precursorEngaged individualsBehavioral impairmentsFacial featuresSerotonergic functioningStimulus animalsRole of serotoninPupil sizeAnxietyPsychiatric disordersSerotonin neurochemistrySerotoninergic functionSerotonin effectsCSF concentrations