2010
Slowly Progressive Axonal Degeneration in a Rat Model of Chronic, Nonimmune-Mediated Demyelination
Wilkins A, Kondo Y, Song J, Liu S, Compston A, Black J, Waxman S, Duncan I. Slowly Progressive Axonal Degeneration in a Rat Model of Chronic, Nonimmune-Mediated Demyelination. Journal Of Neuropathology & Experimental Neurology 2010, 69: 1256-1269. PMID: 21107138, DOI: 10.1097/nen.0b013e3181ffc317.Peer-Reviewed Original ResearchConceptsCentral nervous systemAxonal lossAxonal degenerationAxonal pathologyTrophic supportEarly axonal lossProgressive axonal lossProgressive axonal degenerationWhite matter tractsTaiep mutant ratNerve countsWild-type controlsChronic demyelinationNeurologic disabilityMyelin lossSignificant inflammationRat modelOligodendrocyte dysfunctionImmunohistochemical analysisTaiep ratsNervous systemCNS regionsAxonal transportMutant ratsOligodendrocyte lineage
1993
Protection of the axonal cytoskeleton in anoxic optic nerve by decreased extracellular calcium
Waxman S, Black J, Ransom B, Stys P. Protection of the axonal cytoskeleton in anoxic optic nerve by decreased extracellular calcium. Brain Research 1993, 614: 137-145. PMID: 8348309, DOI: 10.1016/0006-8993(93)91027-p.Peer-Reviewed Original ResearchConceptsArtificial cerebrospinal fluidMin of anoxiaOptic nerveZero-Ca2White matterAnoxic injuryCNS white matter tractAxonal cytoskeletonOptic nerve axonsCNS white matterRat optic nerveInflux of Ca2White matter tractsLoss of cristaeDisorganization of cristaeMembranous profilesUltrastructure of axonsAbnormal influxCerebrospinal fluidExtracellular calciumNerveMyelinated axonsNerve axonsNormal Ca2Axons
1985
Membrane structure of vesiculotubular complexes in developing axons in rat optic nerve: freeze—fracture evidence for sequential membrane assembly
Waxman S, Black J. Membrane structure of vesiculotubular complexes in developing axons in rat optic nerve: freeze—fracture evidence for sequential membrane assembly. Proceedings Of The Royal Society B 1985, 225: 357-363. PMID: 2865731, DOI: 10.1098/rspb.1985.0066.Peer-Reviewed Original Research
1976
Ultrastructure of visual callosal axons in the rabbit
Waxman S, Swadlow H. Ultrastructure of visual callosal axons in the rabbit. Experimental Neurology 1976, 53: 115-127. PMID: 964332, DOI: 10.1016/0014-4886(76)90287-9.Peer-Reviewed Original Research
1972
MORPHOLOGICAL CORRELATES OF FUNCTIONAL DIFFERENTIATION OF NODES OF RANVIER ALONG SINGLE FIBERS IN THE NEUROGENIC ELECTRIC ORGAN OF THE KNIFE FISH STERNARCHUS
Waxman S, Pappas G, Bennett M. MORPHOLOGICAL CORRELATES OF FUNCTIONAL DIFFERENTIATION OF NODES OF RANVIER ALONG SINGLE FIBERS IN THE NEUROGENIC ELECTRIC ORGAN OF THE KNIFE FISH STERNARCHUS. Journal Of Cell Biology 1972, 53: 210-224. PMID: 5013596, PMCID: PMC2108696, DOI: 10.1083/jcb.53.1.210.Peer-Reviewed Original ResearchConceptsNodes of RanvierTypical nodeMorphological correlatesSurface areaMicroSingle nerve fibersElectron microscopyLarge nodesPacked layerSeries capacitySpinal neuronsTypical structureNerve fibersElectric organLevel of entrySingle fiberMembrane surface areaNeural originRunning segmentsAxonsNodal morphologyFiber axisFibersTypical appearanceUnique neural systems