Chapter 5 Electrophysiologic Consequences of Myelination
Waxman S, Bangalore L. Chapter 5 Electrophysiologic Consequences of Myelination. 2004, 117-141. DOI: 10.1016/b978-012439510-7/50058-9.Peer-Reviewed Original ResearchImpulse conductionConduction abnormalitiesDemyelinated axonsRole of demyelinationRestoration of conductionTotal conduction blockNew therapeutic interventionsHigh-frequency trainsEntire myelin sheathMyelin lossClinical deficitsElectrophysiologic consequencesConduction blockPharmacological modulationConduction velocityTherapeutic interventionsAction potentialsDemyelinationMyelin sheathAxonsMolecular substratesSymptom productionAxonal membraneAbnormalitiesCurrent strategies