2015
Erasure of fear memories is prevented by Nogo Receptor 1 in adulthood
Bhagat SM, Butler SS, Taylor JR, McEwen BS, Strittmatter SM. Erasure of fear memories is prevented by Nogo Receptor 1 in adulthood. Molecular Psychiatry 2015, 21: 1281-1289. PMID: 26619810, PMCID: PMC4887429, DOI: 10.1038/mp.2015.179.Peer-Reviewed Original ResearchConceptsPost-traumatic stress disorderExtinction trainingFear memorySpontaneous fear recoveryBasolateral amygdalaJuvenile rodentsFear recoveryFear renewalFear extinctionFear expressionInhibitory synapse markersNgR1 expressionStress disorderNogo receptor 1Anxiety disordersInfralimbic cortexCritical periodNeural plasticityMemoryTemporary windowsReceptor 1TrainingAdulthoodNgR1 functionNaive mice
2013
Anatomical Plasticity of Adult Brain Is Titrated by Nogo Receptor 1
Akbik FV, Bhagat SM, Patel PR, Cafferty WB, Strittmatter SM. Anatomical Plasticity of Adult Brain Is Titrated by Nogo Receptor 1. Neuron 2013, 77: 859-866. PMID: 23473316, PMCID: PMC3594793, DOI: 10.1016/j.neuron.2012.12.027.Peer-Reviewed Original ResearchConceptsNgr1-/- miceNogo receptor 1Somatosensory cortexReceptor 1Adult cerebral cortexDendritic spine turnoverDendritic spine dynamicsAnatomical plasticityCerebral cortexControl miceSpine turnoverAxonal varicositiesWhisker removalAdult brainDendritic spinesSpine dynamicsNull miceAge 26Synaptic turnoverAnatomical connectivityConditional deletionMiceLower set pointNgR1Cortex