2019
Derived esterase activity in Drosophila sechellia contributes to evolved octanoic acid resistance
Lanno S, Coolon J. Derived esterase activity in Drosophila sechellia contributes to evolved octanoic acid resistance. Insect Molecular Biology 2019, 28: 798-806. PMID: 30977928, DOI: 10.1111/imb.12587.Peer-Reviewed Original ResearchConceptsDetoxification gene familiesD. sechelliaGene familyOA resistanceGenomic regionsToxin resistanceMajor-effect lociMedium-chain fatty acids octanoic acidSynergists diethyl maleateDrosophila sechelliaChromosome 3RDefence compoundsEffect lociSechelliaOctanoic acidHost plantsGenetic basisCytochrome P450 enzymatic activityEnzymatic activityMorinda citrifoliaHexanoic acidAcid resistanceGlutathione-S-transferaseEsterase activityToxin
2017
Analysis of cytochrome P450 contribution to evolved plant toxin resistance in Drosophila sechellia
Peyser R, Lanno S, Shimshak S, Coolon J. Analysis of cytochrome P450 contribution to evolved plant toxin resistance in Drosophila sechellia. Insect Molecular Biology 2017, 26: 715-720. PMID: 28703934, DOI: 10.1111/imb.12329.Peer-Reviewed Original ResearchConceptsD. sechelliaDrosophila sechelliaToxin resistanceCytochrome P450 enzymatic activityEnzymatic activityCytochrome P450 gene familyP450 gene familyM. citrifolia fruitDrosophila simulansGenetic mapDrosophila melanogasterDefence compoundsGene familyBasal resistanceHost plantsGenetic basisSpecies of fruit fliesFruit flyFunctional studiesSechelliaGenesLociCytochromePrimary toxinToxin