2021
Genomics analysis of hexanoic acid exposure in Drosophila species
Drum Z, Lanno S, Gregory S, Shimshak S, Ahamed M, Barr W, Bekele B, Biester A, Castro C, Connolly L, DelGaudio N, Humphrey W, Karimi H, Karolczak S, Lawrence T, McCracken A, Miller-Medzon N, Murphy L, Park C, Park S, Qiu C, Serra K, Snyder G, Strauss A, Tang S, Vyzas C, Coolon J. Genomics analysis of hexanoic acid exposure in Drosophila species. G3: Genes, Genomes, Genetics 2021, 12: jkab354. PMID: 34718544, PMCID: PMC8727985, DOI: 10.1093/g3journal/jkab354.Peer-Reviewed Original ResearchConceptsD. sechelliaDrosophila sechelliaSets of differentially expressed genesSpecialist D. sechelliaFruit of Morinda citrifoliaDifferentially expressed genesAcid resistanceHexanoic acidM. citrifolia fruitDrosophila speciesD. melanogasterGeneralist speciesGenomic analysisFruit of M. citrifoliaCandidate genesDietary specialistsDietary specializationTranscriptional responseEcological communitiesTrophic interactionsHost plantsGenetic basisRNA sequencingDownregulated genesGene expression
2017
Analysis of cytochrome P450 contribution to evolved plant toxin resistance in Drosophila sechellia
Peyser R, Lanno S, Shimshak S, Coolon J. Analysis of cytochrome P450 contribution to evolved plant toxin resistance in Drosophila sechellia. Insect Molecular Biology 2017, 26: 715-720. PMID: 28703934, DOI: 10.1111/imb.12329.Peer-Reviewed Original ResearchConceptsD. sechelliaDrosophila sechelliaToxin resistanceCytochrome P450 enzymatic activityEnzymatic activityCytochrome P450 gene familyP450 gene familyM. citrifolia fruitDrosophila simulansGenetic mapDrosophila melanogasterDefence compoundsGene familyBasal resistanceHost plantsGenetic basisSpecies of fruit fliesFruit flyFunctional studiesSechelliaGenesLociCytochromePrimary toxinToxin