2019
Investigating the role of Osiris genes in Drosophila sechellia larval resistance to a host plant toxin
Lanno S, Shimshak S, Peyser R, Linde S, Coolon J. Investigating the role of Osiris genes in Drosophila sechellia larval resistance to a host plant toxin. Ecology And Evolution 2019, 9: 1922-1933. PMID: 30847082, PMCID: PMC6392368, DOI: 10.1002/ece3.4885.Peer-Reviewed Original ResearchOA resistanceAdaptive phenotypic changesResistant to OAGenomic regionsGenetic basisGenome-wide differential gene expressionPhenotypic changesToxic host plantsFine-mapping QTLDifferential gene expressionHost plant toxinsMultiple life stagesOsiris genesLife stagesGenetic mapHost specializationFamily genesHost plantsResistance genesRNA sequencingRNA interferenceExposure to OAGene expressionGenesFruit fly
2017
Analysis of cytochrome P450 contribution to evolved plant toxin resistance in Drosophila sechellia
Peyser R, Lanno S, Shimshak S, Coolon J. Analysis of cytochrome P450 contribution to evolved plant toxin resistance in Drosophila sechellia. Insect Molecular Biology 2017, 26: 715-720. PMID: 28703934, DOI: 10.1111/imb.12329.Peer-Reviewed Original ResearchConceptsD. sechelliaDrosophila sechelliaToxin resistanceCytochrome P450 enzymatic activityEnzymatic activityCytochrome P450 gene familyP450 gene familyM. citrifolia fruitDrosophila simulansGenetic mapDrosophila melanogasterDefence compoundsGene familyBasal resistanceHost plantsGenetic basisSpecies of fruit fliesFruit flyFunctional studiesSechelliaGenesLociCytochromePrimary toxinToxin