2006
Use of Vaginally Administered Chlorhexidine During Labor to Improve Pregnancy Outcomes
Goldenberg RL, McClure EM, Saleem S, Rouse D, Vermund S. Use of Vaginally Administered Chlorhexidine During Labor to Improve Pregnancy Outcomes. Obstetrics And Gynecology 2006, 107: 1139-1146. PMID: 16648420, DOI: 10.1097/01.aog.0000215000.65665.dd.Peer-Reviewed Original ResearchConceptsPregnancy outcomesHuman immunodeficiency virusExcellent safety profileGroup B streptococciUse of chlorhexidineChild transmissionNeonatal sepsisNeonatal infectionChlorhexidine useVaginal treatmentImmunodeficiency virusNeonatal mortalityPregnant womenSafety profileAdverse outcomesNewborn periodSTUDY SELECTIONB streptococciPromising treatmentChlorhexidine treatmentBacterial loadChlorhexidineEffective killersEnglish literatureFurther studies
2004
Tolerance and Safety of Different Concentrations of Chlorhexidine for Peripartum Vaginal and Infant Washes: HIVNET 025
Wilson CM, Gray G, Read JS, Mwatha A, Lala S, Johnson S, Violari A, Sibiya PM, Fleming TR, Koonce A, Vermund SH, McIntyre J. Tolerance and Safety of Different Concentrations of Chlorhexidine for Peripartum Vaginal and Infant Washes: HIVNET 025. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2004, 35: 138-143. PMID: 14722445, PMCID: PMC2753236, DOI: 10.1097/00126334-200402010-00006.Peer-Reviewed Original ResearchConceptsChris Hani Baragwanath HospitalPrevention of motherHIV Type 1Solution of chlorhexidineConcentrations of chlorhexidineChild transmissionBaragwanath HospitalMaternal symptomsPrevention trialsThird trimesterClinical indicationsMaternity unitsSubjective complaintsVaginal areaWash groupType 1ChlorhexidineInfant examinationWomenSustainable interventionsTolerable concentrationInterventionMothersWashDifferent concentrations
2002
Lack of Effect of Chlorhexidine Varnish on Streptococcus mutans Transmission and Caries in Mothers and Children
Dasanayake AP, Wiener HW, Li Y, Vermund S, Caufield PW. Lack of Effect of Chlorhexidine Varnish on Streptococcus mutans Transmission and Caries in Mothers and Children. Caries Research 2002, 36: 288-293. PMID: 12218279, DOI: 10.1159/000063922.Peer-Reviewed Original ResearchConceptsChlorhexidine varnishSalivary S. mutans levelsChild's fourth birthdayRandomized clinical trialsS. mutans levelsMother-child pairsFourth birthdayMother-child transmissionS. mutans colonizationLack of effectCaries experienceMutans levelsPlacebo varnishClinical trialsFirst babyTreatment groupsControl groupWeekly intervalsCariesMothersChildrenMonthsStreptococcus mutansGroupBabies