Prevalence and predictors of intestinal helminth infections among human immunodeficiency virus type 1-infected adults in an urban African setting.
Modjarrad K, Zulu I, Redden DT, Njobvu L, Freedman DO, Vermund SH. Prevalence and predictors of intestinal helminth infections among human immunodeficiency virus type 1-infected adults in an urban African setting. American Journal Of Tropical Medicine And Hygiene 2005, 73: 777-82. PMID: 16222025, PMCID: PMC2749260, DOI: 10.4269/ajtmh.2005.73.777.Peer-Reviewed Original ResearchConceptsHIV-1-infected adultsIntestinal helminth infectionsHelminth infectionsUrban African settingIntestinal helminthsHuman immunodeficiency virus type 1Immunodeficiency virus type 1Detrimental immunologic effectsRoutine HIV careAfrican settingHuman immunodeficiency virusLight-intensity infectionsHIV infection ratesVirus type 1HIV careImmunologic effectsConcomitant infectionImmunodeficiency virusPrior historyHelminth diagnosisAscaris lumbricoidesHelminth statusParasitologic dataInfection rateInfectionTreatment of Intestinal Helminths Does Not Reduce Plasma Concentrations of HIV-1 RNA in Coinfected Zambian Adults
Modjarrad K, Zulu I, Redden DT, Njobvu L, Lane HC, Bentwich Z, Vermund SH. Treatment of Intestinal Helminths Does Not Reduce Plasma Concentrations of HIV-1 RNA in Coinfected Zambian Adults. The Journal Of Infectious Diseases 2005, 192: 1277-1283. PMID: 16136473, PMCID: PMC2730764, DOI: 10.1086/444543.Peer-Reviewed Original ResearchConceptsHIV-1 RNAViral loadPlasma concentrationsAntihelminthic treatmentCopies/Helminth infectionsIntestinal helminthsHigh pretreatment viral loadMedian baseline viral loadPretreatment viral loadBaseline viral loadDysfunctional immune responseIntestinal helminth infectionsHuman immunodeficiency virusMean viral loadCopies/mLHigher helminth burdensPosttreatment visitAsymptomatic adultsImmunodeficiency virusProspective studyZambian adultsUninfected groupHIV-1Immune response