2012
Oral Lesions: Poor Markers of Virologic Failure in HIV‐Infected Patients on Antiretroviral Therapy
Tami-Maury I, Willig J, Jolly P, Vermund S, Aban I, Hill J, Wilson C. Oral Lesions: Poor Markers of Virologic Failure in HIV‐Infected Patients on Antiretroviral Therapy. International Scholarly Research Notices 2012, 2013: 1-7. DOI: 10.5402/2013/269728.Peer-Reviewed Original ResearchPositive predictive valueVirologic failureAntiretroviral therapyPredictive valueViral loadHigh baseline viral loadMonths of ARTModerate positive predictive valueBaseline viral loadStrong positive predictive valueNegative predictive valueVirologic statusBaseline factorsCopies/Poor markerPatientsMental disordersOL groupTherapyMonthsHIVArt therapyPoor predictorMarkersFailure
2008
Simple Adherence Assessments to Predict Virologic Failure among HIV-Infected Adults with Discordant Immunologic and Clinical Responses to Antiretroviral Therapy
Goldman JD, Cantrell RA, Mulenga LB, Tambatamba BC, Reid SE, Levy JW, Limbada M, Taylor A, Saag MS, Vermund SH, Stringer JS, Chi BH. Simple Adherence Assessments to Predict Virologic Failure among HIV-Infected Adults with Discordant Immunologic and Clinical Responses to Antiretroviral Therapy. AIDS Research And Human Retroviruses 2008, 24: 1031-1035. PMID: 18724803, PMCID: PMC2747786, DOI: 10.1089/aid.2008.0035.Peer-Reviewed Original ResearchConceptsMedication possession ratioVirologic failureOptimal adherenceSuboptimal adherenceTreatment failurePoor adherenceLow medication possession ratioDetectable HIV viremiaProportion of patientsSubset of patientsViral load measurementsART initiationHIV viremiaAntiretroviral therapyDetectable viremiaClinical responseDrug adherencePossession ratioMedian timeMissed doseImmunologic responseTreatment courseAdherence assessmentCopies/Patients
2005
Treatment of Intestinal Helminths Does Not Reduce Plasma Concentrations of HIV-1 RNA in Coinfected Zambian Adults
Modjarrad K, Zulu I, Redden DT, Njobvu L, Lane HC, Bentwich Z, Vermund SH. Treatment of Intestinal Helminths Does Not Reduce Plasma Concentrations of HIV-1 RNA in Coinfected Zambian Adults. The Journal Of Infectious Diseases 2005, 192: 1277-1283. PMID: 16136473, PMCID: PMC2730764, DOI: 10.1086/444543.Peer-Reviewed Original ResearchConceptsHIV-1 RNAViral loadPlasma concentrationsAntihelminthic treatmentCopies/Helminth infectionsIntestinal helminthsHigh pretreatment viral loadMedian baseline viral loadPretreatment viral loadBaseline viral loadDysfunctional immune responseIntestinal helminth infectionsHuman immunodeficiency virusMean viral loadCopies/mLHigher helminth burdensPosttreatment visitAsymptomatic adultsImmunodeficiency virusProspective studyZambian adultsUninfected groupHIV-1Immune response
2001
Virologic and Immunologic Determinants of Heterosexual Transmission of Human Immunodeficiency Virus Type 1 in Africa
Fideli L, Allen S, Musonda R, Trask S, Hahn B, Weiss H, Mulenga J, Kasolo F, Vermund S, Aldrovandi G. Virologic and Immunologic Determinants of Heterosexual Transmission of Human Immunodeficiency Virus Type 1 in Africa. AIDS Research And Human Retroviruses 2001, 17: 901-910. PMID: 11461676, PMCID: PMC2748905, DOI: 10.1089/088922201750290023.Peer-Reviewed Original ResearchConceptsCopies/Heterosexual transmissionRisk ratioMultivariate Cox regression analysisHuman immunodeficiency virus type 1Immunodeficiency virus type 1Plasma viral loadCox regression analysisCorresponding risk ratioHIV-1 RNAVirus type 1Female transmissionCase-control designGender-specific differencesPlasma VLImmunologic correlatesViral loadProspective studySerology resultsWorld's HIVVirus isolationType 1Immunologic determinantsReference groupNontransmitters