Orexin-A Suppresses Signal Transmission to Dopaminergic Amacrine Cells From Outer and Inner Retinal Photoreceptors
Qiao SN, Zhou W, Liu LL, Zhang DQ, Zhong YM. Orexin-A Suppresses Signal Transmission to Dopaminergic Amacrine Cells From Outer and Inner Retinal Photoreceptors. Investigative Ophthalmology & Visual Science 2017, 58: 4712-4721. PMID: 28910447, PMCID: PMC5598320, DOI: 10.1167/iovs.17-21835.Peer-Reviewed Original ResearchConceptsDopaminergic amacrine cellsInner retinal photoreceptorsOrexin receptorsAmacrine cellsVisual functionRetinal photoreceptorsWhole-cell voltage-clamp techniqueOuter retinal photoreceptorsVoltage-clamp techniqueNeuropeptide orexinEndogenous orexinsDopaminergic systemUpstream neuronsOrexinCone functionMammalian retinaMouse retinaGenetic deletionRetinaVertebrate retinaIpRGCsReceptorsLight-induced responsesPhotoreceptorsResponse