Linkage disequilibrium in the human genome
Reich D, Cargill M, Bolk S, Ireland J, Sabeti P, Richter D, Lavery T, Kouyoumjian R, Farhadian S, Ward R, Lander E. Linkage disequilibrium in the human genome. Nature 2001, 411: 199-204. PMID: 11346797, DOI: 10.1038/35075590.Peer-Reviewed Original ResearchMeSH KeywordsAllelesBiasChromosome MappingComputer SimulationEuropeFounder EffectGenetic Diseases, InbornGenome, HumanHaplotypesHeterozygoteHumansLinkage DisequilibriumModels, GeneticNigeriaPhylogenyPolymorphism, Single NucleotideRacial GroupsRecombination, GeneticReproducibility of ResultsSelection, GeneticTime FactorsUnited StatesConceptsLinkage disequilibriumGenome-wide mapsAncestral chromosomesGenomic regionsHuman genomeSingle nucleotide polymorphismsLD mappingDemographic eventsLD blocksCommon SNPsHuman geneticsNucleotide polymorphismsCommon allelesDifferent populationsAllelesNorth European descentDisequilibriumGenomeKilobasesChromosomesNorthern EuropeansGenesLociGeneticsKb